
Epigenetics
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Chromatin Analysis
Epitranscriptome Analysis
DNA Methylation Analysis
Methylome Analysis
Methyltransferases for Epigenetics
Hydroxymethylation Detection and Analysis
Analysis of DNA Methylation by Bisulfite Conversion
Enrichment
Enzymatic Conversion for DNA Methylation Analysis
Methylation Sensitive and Methylation Dependent Restriction Enzymes for Epigenetics
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Enzymatic Methyl-seq: The Next Generation of Methylome Analysis
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Epigenetics - Expanding on Genomic Foundations
- Epigenetics Brochure
- Restriction Enzymes for Epigenetics Selection Chart
- EpiMark® Methylated DNA Enrichment Kit Troubleshooting Guide
Feature Articles
Brochures
Selection Tools
Troubleshooting Guides
- Diep, D. and Zhang, K. (2011) Genome-wide mapping of the sixth base Genome Biol; 12, 116. PubMedID: 21682934, DOI: 10.1186/gb-2010-12-6-116
- Ficz, G., et al. (2011) Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation Nature; PubMedID: 21460836, DOI: 10.1038/nature10008
- Stroud, H., et al. (2011) 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells Genome Biol; PubMedID: 21689397
- Wolff, E.M. et al. (2011) Hypomethylation of a LINE-1 Promoter Activates an Alternate Transcript of the MET Oncogene in Bladders with Cancer PLoS Genet; 6, 4:e1000917 . PubMedID: 20421991
- Wang, H., Guan, S., Quimby, A., Cohen-Karni, D., Pradhan, S., Wilson, G.G., Roberts, R.J., Zhu, Z.and Zheng, Y. (2011) Comparitive characterization of the PvuRts11 family and application in mapping genomic 5-hydroxymethylcytosine Nucleic Acids Res; PubMedID: 21813453, DOI: 10.1093/nar/gkr607
- Cohen-Karni, D, et al. (2011) The MspJI family of modification-dependent restriction endonucleases for epigenetic studies Proc Natl Acad Sci U S A; PubMedID: 21690366, DOI: 10.1073/pnas.1018448108
- Kinney, S. M., Chin, H. G., Vaisvila, R., Bitinaite, J., Zheng, Y., Estève, P. O., Feng, S., Stroud, H., Jacobsen, S. E., Pradhan, S. (2011) Tissue specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genome J Biol Chem; 286:28, 24685–2469. PubMedID: 21610077
- Canc. Res. (2011) 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1 Cancer Res; 71, 1904-1911. PubMedID: 21239472
- Zhang, J. et al. (2011) Cyclophosphamide perturbs cytosine methylation in jurkat-T Cells through LSD1-mediated stabilization of DNMT1 Protein Chem Res Toxicol; PubMedID: 22007908
- Nelson, F.K, Snyder, M., Gardner, A.F., Hendrickson, C.L., Shendure, J.A., Porreca, G.J., Church, G.M., Ausubel, F.M., Ju, J., Kieleczawa, J. and Slatko, B.E (2011) Introduction and historical overview of DNA sequencing Curr Protoc Mol Biol; Unit 7.0.1-7.0.18., PubMedID: 21987056
- Mooijman D, Dey S S, Boisset JC, Crosetto N, van Oudenaarden A (2016) Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction Nat Biotechnol; 34, 852-857. PubMedID: 27347753, DOI: 10.1038/nbt.3598
- Page A., Paoli P., Salvador E., White S., French J., Mann J. (2015) Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape J Hepatol; PubMedID: 26632634, DOI: 10.1016/j.jhep.2015.11.024
- Gong, H. wt al. (2012) Near-infrared fluorescence imaging of mammalian cells and xenograft tumors with SNAP-tag PLoS One; 7, PubMedID: 22479502
- Ho, J.J., et al. (2012) Functional importance of Dicer protein in the adaptive cellular response to hypoxia J Biol Chem; 17, 29003-20. PubMedID: 22745131, DOI: 10.174/jbcM112.373365
- Grant, T.J., et al. (2012) Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma Proc Natl Acad Sci U S A; 109, 4503-4508. PubMedID: 22396589
- Foraker, A.B., et al. (2012) Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG J Cell Biol; 198, 591-605.
- Gu, L.Q., et al. (2012) Detection of miRNAs with a nanopore single-molecule counter Expert Rev Mol Diagn; 12, 573-584. PubMedID: 22845478
- Sexton T, Kurukuti S, Mitchell JA, Umlauf D, Nagano T, Fraser P (2012) Sensitive detection of chromatin coassociations using enhanced chromosome conformation capture on chip Nat Protoc; 7(7), 1335-50. PubMedID: 22722369, DOI: 10.1038/nprot.2012.071
- Wee E., Ngo T., Trau M. (2015) A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation Sci Rep; 5, 15028. PubMedID: 26458746, DOI: 10.1038/srep15028
- Chernov AV., Reyes L., Peterson S., Strongin AY. (2015) Depletion of CG-Specific Methylation in Mycoplasma hyorhinis Genomic DNA after Host Cell Invasion PLoS One; 10, e0142529. PubMedID: 26544880, DOI: 10.1371/journal.pone.0142529
- Kienhöfer S., Musheev M., Stapf U., Helm M., Schomacher L., Niehrs C., Schäfer A. (2015) GADD45a physically and functionally interacts with TET1Publication Differentiation; PubMedID: 26546041, DOI: 10.1016/j.diff.2015.10.003
- Zheng, Y. et al. (2010) A unique family of Mrr-like modification-dependent restriction endonucleases Nucleic Acids Res; 38(16), 5527-5534. PubMedID: 20444879
- Wanunu, M. et al. (2010) Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecular J Am Chem Soc; 133(3), PubMedID: 21155562
- Wanunu, M., et al. (2010) Rapid electronic detection of probe-specific microRNAs using thin nanopore sensors Nat Nanotechnol; 5, 807-814. PubMedID: 20972437
- Laget, S., et al. (2010) The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA PLoS One; 5, PubMedID: 20700456
- Jensen, H.M., et al. (2010) Engineering of a synthetic electron conduit in living cells Proc Natl Acad Sci U S A; 107, 19213-19218. PubMedID: 20956333
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