PleI
neb31 cloned at NEB recombinant 2site dil_A 37 65 Heat CpG

PleI has been reformulated with Recombinant Albumin (rAlbumin) beginning with Lot #10141295. Learn more.

We are excited to announce that all reaction buffers are now BSA-free. NEB began switching our BSA-containing reaction buffers in April 2021 to buffers containing Recombinant Albumin (rAlbumin) for restriction enzymes and some DNA modifying enzymes. Find more details at www.neb.com/BSA-free.


NEB restriction endonuclease that recognizes the sequence GAGTCNNNN^N_
  • 100% activity in rCutSmart Buffer (over 210 enzymes are available in the same buffer) allowing for easier double digests
  • Type IIS restriction enzymes recognize asymmetric DNA sequences and cleave outside of their recognition sequence

  • Requires two or more sites for cleavage. Please review the enzyme list and recommendations in the following table as well as the background information article.

  • Restriction Enzyme Cut Site: GAGTC(4/5)

Catalog # Concentration Size List Price Your Price Quantity
R0515S 5,000 units/ml 1,000 units $75.00
Please enter a quantity for at least one size
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