Sce PUS1
neb31 cloned at NEB recombinant 30 55 Heat

We are excited to announce that all reaction buffers are now BSA-free. NEB began switching our BSA-containing reaction buffers in April 2021 to buffers containing Recombinant Albumin (rAlbumin) for restriction enzymes and some DNA modifying enzymes. Find more details at

  • Sce PUS1 isomerizes uridine to pseudouridine in predominantly single-stranded RNA in vitro
  • Sce PUS1 is a stand-alone enzyme and does not require an RNA guide or co-factor to modify RNA
  • Sequence-specific pseudouridine modification by Sce PUS1 is an alternative to randomly incorporated modified nucleosides by RNA polymerases

This is an Enzyme for Innovation (EFI). EFI is a project initiated by NEB to provide unique enzymes to the scientific community in the hopes of enabling the discovery of new and innovative applications. These enzymes have interesting properties and unique specificities.

Catalog # Concentration Size List Price Your Price Quantity
M0526S 100 pmol/μl 5,000 pmol $85.00
Please enter a quantity for at least one size
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