Q5® High-Fidelity DNA Polymerase
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Fidelity at its finest.

Q5® High-Fidelity DNA Polymerase sets a new standard for both fidelity and robust performance. With the highest fidelity amplification available (~280 times higher than Taq), Q5 DNA Polymerase results in ultra-low error rates. Q5 DNA Polymerase is composed of a novel polymerase that is fused to the processivity-enhancing Sso7d DNA binding domain, improving speed, fidelity and reliability of performance. 

  • Highest fidelity amplification (~280X higher than Taq)
  • Ultra-low error rates
  • Superior performance for a broad range of amplicons (from high AT to high GC)
  • Hot start and master mix formats available
Learn more about how this product is being used in the Product Citation Tool
Catalog # Concentration Size List Price Your Price Quantity
M0491S 2,000 units/ml 100 units $108.00
M0491L 2,000 units/ml 500 units $432.00
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Want to try this product? Request a sample Interested in glycerol-free or custom formulations? – contact our Custom Solutions Group

NEB provides bulk and custom versions of our products. Options include changes in concentration, formulation or optimization for use in third party products. Bulk packaging may also be appropriate for large recurring orders. Learn More


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