Histone H4 Human, Recombinant
Histone H4 combines with Histone H3 to form the H3/H4 tetramer. Histone H4 is also modified by various enzymes and these modifications have been shown to be important in gene regulation.
- Highly pure, recombinant protein
- Identity confirmed using Edman Degradation to sequence intact protein
- Mass confirmed by ESI-TOF MS
- Tested for exonuclease, endonuclease and protease contamination
Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer (1,2). Histone H4 is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.
SGRGK GGKGL GKGGA KRHRK VLRDN IQGIT KPAIR RLARR GGVKR ISGLI YEETR GVLKV FLENV IRDAV TYTEH AKRKT VTAMD VVYAL KRQGR TLYGF GG (Genbank accession number: AAM83108)
Product SourceAn E. coli strain that carries a plasmid encoding the cloned human histone H4 gene, HIST2H4. (Genbank accession number: AF525682)
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