T4 RNA Ligase 1 (ssRNA Ligase)

There is also a high concentration (30,000 units/ml) version of this enzyme available, T4 RNA Ligase 1 (ssRNA Ligase), High Concentration (NEB #M0437M).

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T4 RNA Ligase 1 catalyzes the ligation of a 5' phosphoryl-terminated nucleic acid to a 3' hydroxyl-terminated nucleic acid. Substrates include single-stranded RNA and DNA, as well as dinucleoside pyrophosphates.

  • Ligation of ss-RNA and DNA
  • Labeling of 3'-termini of RNA with 5'-[32P] pCp
  • Synthesis of single-stranded oligodeoxyribo-nucleotides
  • Recombinant enzyme supplied with 10X Reaction Buffer, ATP and PEG
  • Tested for the absence of endonucleases, exonocleases and RNases
  • Not sure which ligase to choose? Refer to our DNA and RNA Ligase Properties Chart

Ordering Information

  • 10,000 units/ml
    1,000 units
  • 10,000 units/ml
    5,000 units
Did you know this product can be customized or purchased in larger volumes? Submit an inquiry to find out more about customization options.
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