SNAP-Capture Magnetic Beads

The SNAP-Capture Magnetic Beads are used to selectively immobilize and magnetically separate a SNAP-tag fusion protein from solution using magnetic agarose beads.  They are prepared by the coupling of SNAP-tag® substrate benzylguanine with highly stable 75-150 µm superparamagnetic particles.

  • These beads show a low non-specific absorption of proteins from a complex lysate
  • They are suitable for pull down applications

Ordering Information

$name
  • 2 ml
    $205.00
  • Product Information
    Two ml of SNAP-Capture Magnetic Beads is sufficient to perform 25 immobilization assays using 80 µl of bead suspension per assay.

    The SNAP-tag is a novel tool for protein research, allowing the specific, covalent attachment of virtually any molecule or modified surface to a protein of interest. The SNAP-tag is a protein based on mammalian O6-alkylguanine-DNA-alkyltransferase (AGT).  SNAP-tag substrates are derivatives of benzyl purines and benzyl pyrimidines.  In the immobilization reaction, the SNAP-tag is covalently attached to the substituted benzyl group of the SNAP-Capture Magnetic Beads.

    There are two steps to using this system: sub-cloning and expression of the protein of interest as a SNAP-tag fusion, and capture and immobilization of the fusion protein using SNAP-Capture Magnetic Beads.

    Figure 1: Substrate structure on SNAP-Capture Magnetic Beads 
    Figure 1: Substrate structure on SNAP-Capture Magnetic Beads

    Product Categories:
    SNAP-Capture Products,
    Magnetic Matrices & Racks,
    Proteome Analysis
    ,
    SNAP-tag Substrates
    ,
    Protein Labeling Products
    Applications:
    Pull-down Assays,
    Affinity Purification,
    Cell Imaging
    ,
    Protein Labeling (SNAP/CLIP)
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