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Histone H3.2 is an H3 variant that is found in all eukaryotes, except budding yeast. It is replication-dependent and is associated with gene silencing.
Highly pure, recombinant protein
Identity confirmed using Edman Degradation to sequence intact protein; mass confirmed by ESI-TOF MS
Tested for exonuclease, endonuclease and protease contamination
Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. It is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.
1 mg/ml, 66 µM is calculated using the molar extinction coefficient for Histone H3.2 (3960) and its absorbance at 280 nm (4,5). 1.0 A280 units = 3.9 mg/ml
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