Histone H3.2 Human, Recombinant
Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. It is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation. Histone H3.2, an H3 variant that is found in all eukaryotes except budding yeast, is replication dependent and is associated with gene silencing.
Protein Sequence: ARTKQ TARKS TGGKA PRKQL ATKAA RKSAP ATGGV KKPHR YRPGT VALRE IRRYQ KSTEL LIRKL PFQRL VREIA QDFKT DLRFQ SSAVM ALQEA SEAYL VGLFE DTNLC AIHAK RVTIM PKDIQ LARRI RGERA (Genbank accession number: Q71DI3)
Product SourceAn E.coli strain that carries a plasmid encoding the cloned human histone H3.2 gene, HIST2H3A or HIST2H3C. (Genbank accession number: BC130637)
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