Human Alkyladenine DNA Glycosylase (hAAG) excises alkylated and oxidative DNA damaged sites, including 3-methyladenine, 7-methylguanine, 1,N6-ethenoadenine and hypoxanthine. hAAG catalyzes the hydrolysis of the N-glycosidic bond to release the damaged base. hAAG is also known as methylpurine DNA glycosylase (MPG) (1,2,3) or 3-methyladenine-DNA glycosylase (ANPG) (4).
Product SourceAn E. coli strain which carries the cloned truncated human AAG gene (1)
The following reagents are supplied with this product:
Store at (°C) Concentration ThermoPol® Reaction Buffer Pack -20 10 X
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