Human DNA (cytosine-5) Methyltransferase (Dnmt1)
Dnmt1 methylates cytosine residues in hemimethylated DNA in the sequence of 5'...CG...3' (1,2). Mammalian Dnmt1 is believed to be involved in carcinogenesis, embryonic development and several other biological functions (3-5).
The bulk of the methylation takes place during DNA replication in the S-phase of the cell cycle (6).
Product SourceDnmt1 is expressed from human Dnmt1 cDNA using a baculovirus expression system (1,7).
The following reagents are supplied with this product:
Store at (°C) Concentration Dnmt1 Reaction Buffer -20 10 X Purified BSA -20 S-adenosylmethionine (SAM) -20 32 mM
- FAQs & Tech Tips
- Protocols & Manuals
- Quality & Safety
- Legal Information
Ineligible item added to cart
Based on your Freezer Program type, you are trying to add a product to your cart that is either not allowed or not allowed with the existing contents of your cart. Please review and update your order accordingly If you have any questions, please contact Customer Service at firstname.lastname@example.org or 1-800-632-5227 x 8.