Solutions for Lyophilization
Lyophilization, or freeze-drying, enables room-temperature storage and transport of temperature-sensitive reagents and assays. Beyond improving shelf life and stability, lyophilized products offer enhanced usability in point-of-care, point-of-use, and field-based settings. Whether you're looking for off-the-shelf lyophilized products, reagents optimized for lyophilization, or custom lyophilization of your own formulation, NEB is here to support your workflow.
NEB has over 50 years of experience in enzyme formulation and extensive expertise in lyophilization; we offer flexible, science-driven lyophilization solutions tailored to your specific goals. Our team has developed and optimized freeze-dried reagents across a wide range of applications, ensuring consistent performance, stability, and ease of use. By combining formulation know-how with lyophilization expertise, NEB offers streamlined, end-to-end solutions from development to delivery backed by the quality and reliability you trust.
Explore our Solutions
- Ready-to-Use Lyophilized Products: We have optimized excipients and drying conditions to ensure our lyophilized products deliver high performance and stability. These ready-to-use formats not only simplify and streamline your workflow, but they also offer a foundation on which you can customize to meet your specific assay needs.
Product Name Application LyoPrime Luna® Probe One-Step RT-qPCR Mix with UDG RT-qPCR LyoPrime WarmStart™ Fluorescent LAMP/RT-LAMP Mix (with UDG) LAMP & RT-LAMP with fluorescent detection LyoPrime WarmStart™ LAMP/RT-LAMP Mix (with UDG)
(Available through Customized Solutions: contact us to order)LAMP & RT-LAMP with alternative detection methods Monarch® DNase I, Lyophilized Nucleic Acid Purification, Cloning, Synthetic Biology - Glycerol-free & Lyo-compatible Reagents: NEB offers a broad selection of reagents in glycerol-free and lyo-compatible formulations to support your lyophilization needs. View some of our most popular products below or access the complete list.
Product Name Recommended Application Bst-XT WarmStart™ DNA Polymerase (Glycerol-free) LAMP Bst 2.0 WarmStart® DNA Polymerase (Glycerol-free) LAMP WarmStart® RTx Reverse Transcriptase (Glycerol-free) RT-LAMP - Custom Lyophilization: When you engage with us for custom lyophilization, we take the time to understand your intended use, workflow, and project objectives. This informs how we approach your formulation and helps guide decisions around format and packaging. Whether you're building on an existing NEB lyophilized product (adding primers or making small adjustments) or developing a completely bespoke formulation, our team is here to support you.
As both the developer and manufacturer of our enzymes, we have unique visibility into formulation and production details, along with direct access to reagents, effectively simplifying supply chain logistics. We also often work with third-party reagents and can source materials from your preferred suppliers.

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Interested in learning more?
Find out how NEB Lyophilization Sciences can support the development of your custom lyophilized assay.
Contact UsLearn More
- NEBTV Webinar: What does the future look like for lyophilized amplification assays
- How Lyophilized Beads Are Changing Diagnostics and Research
- Enhancing Molecular Diagnostics in Regulated Markets with Lyophilized Assays
- Debunking the myths: clearing up six common misconceptions about reagent lyophilization
- Glycerol-free and Lyo-compatible Reagents to Support Diagnostic Assay Developers
- Key considerations for optimal lyophilized reagent development