
Supporting Molecular Diagnostics
The COVID-19 pandemic elevated many of the challenges faced by clinical labs, requiring new and innovative solutions to address them. Technology development is happening faster than ever before, exposing weaknesses in diagnostic supply chains, increasing the need for innovation and thinking differently about how diagnostics should be developed, manufactured and deployed.
Many scientists know NEB as a trusted reagent provider to the life science community. What many do not know is that we also offer a portfolio of products that serve as critical components for a wide array of diagnostic products and services. Extensive molecular biology and enzymology experience provide NEB with the unique ability to help customers solve the challenges inherent in technology development and ultimately in scale-up and commercialization. Further, the acquisition of Fluorogenics™ Limited (FGL), now NEB Lyophilization Sciences™, combines FGL's expertise in lyophilization with NEB’s diverse product portfolio to offer lyophilized and lyo-compatible products and custom services optimized for diagnostic assay and platform developers.
Learn more about the benefits of using lyophilized reagents in our feature article: Enhancing Molecular Diagnostics in Regulated Markets with Lyophilized Assays.
It's time to think differently
Our OEM & Customized Solutions Team has been serving customers for over 30 years. We understand the demands around technology development and product launches, and are able to apply a cross-functional team of scientists and staff to quickly optimize your reagent development. We have made significant investment in our scale-up and manufacturing capabilities, and can offer consistent and reliable supply chain with fair and flexible terms. We have also focused our efforts in project management, operations and fulfillment, positioning us to respond quickly and effectively manage your custom projects. Expansion of our quality, regulatory affairs and quality control infrastructure underscores our commitment to making the best possible products, every time.
Most importantly, we pride ourselves in being a resource to you, not just through our product offering, but through the support that we provide. As one of the few privately held molecular biology tools providers, our goal is to establish partnerships that advance our customer’s science and business objectives. 100% of our production capacity is earmarked for the customers we serve, and not for the manufacture of our own diagnostic products.
What does this all mean for you? If you are looking for reagents to incorporate into your latest technologies, laboratory developed tests (LDTs), CE/IVDs or diagnostic kits for EUA and 510K approval, and see these same challenges and need for change in the molecular diagnostic market, it’s time to think differently and consider NEB as your partner for future assay development and scale up needs.
Select a molecular diagnostic-related application to learn more:

Amplification-based Molecular Diagnostics
NEB has a long history in the development of reliable and convenient tools for amplification, and offers a large selection of products for PCR, qPCR, RT-qPCR and isothermal amplification. Our extensive expertise in this area has allowed us to develop optimized enzymes for a variety of applications, including incorporation into diagnostics. The table below summarizes some of the products available from NEB for diagnostic applications. Bulk and/or custom formats are available for all products, with more specific customization details included below:
Application | Products | Product Notes | Custom Formulations Available | |
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PCR Applications | qPCR/RT-qPCR |
DNA, Dye DNA, Probe |
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RNA (1-step), Dye RNA (1-step), Probe |
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RNA (2-step) |
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PCR/RT-PCR |
Master Mixes Standalone Enzyme & Buffer
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Z05 DNA Polymerase |
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Q5 Blood Direct 2X Master Mix |
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Isothermal Applications | LAMP/RT-LAMP |
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SARS-CoV-2 Rapid Colorimetric LAMP Assay Kit |
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WarmStart LAMP Kit (DNA & RNA) WarmStart Multi-Purpose LAMP/RT-LAMP 2X Master Mix (with UDG) |
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Tte UvrD Helicase |
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Bst 3.0 DNA Polymerase |
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WarmStart RTx Reverse Transcriptase |
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Strand Displacement |
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Helicase-dependent Amplification | IsoAmp® II Universal tHDA Kit |
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Other | Bsu DNA Polymerase, Large Fragment |
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T4 Gene 32 Protein |
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Deoxynucleotide (dNTP) Solution Mix |
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Nuclease-free Water | ||||
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Proteinase K | ||||
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Next Generation Sequencing-based Molecular Diagnostics
Sequencing is enabling scientists to make rapid advances in epidemiology and surveillance, basic and clinical research, and diagnostics. A fast-growing number of methods are being developed to address whole genome, as well as targeted approaches. In all cases, streamlined workflows that result in high-quality, high yield libraries are critical towards optimizing your next generation sequencing (NGS) results. The table below summarizes some of the products available from NEB for diagnostic applications. Bulk and/or custom formats are available for all products, with more specific customization details included below:
Application | Products | Notes | ||
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NGS-based Molecular Diagnostics | DNA Sequencing | DNA library preparation with enzymatic DNA fragmentation |
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DNA library preparation for cfDNA or presheared DNA | ||||
RNA Sequencing | Depletion of abundant RNAs | |||
RNA library preparation |
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Virus sequencing and detection |
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Products and content are covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc (NEB). The use of trademark symbols does not necessarily indicate that the name is trademarked in the country where it is being read; it indicates where the content was originally developed. The use of this product may require the buyer to obtain additional third-party intellectual property rights for certain applications. For more information, please email busdev@neb.com.