T7 Endonuclease I
NEB2 cloned at NEB recombinant 37 No

Authenticase® (NEB #M0689) now available for improved genome editing mutation detection.

  • DNA Endonuclease
  • Catalyzes the cleavage of DNA mismatches and non-β DNA structures including Holliday junctions and cruciform leaving 3'-OH and 5'-phosphate
  • Best at C mismatches and does not recognize all DNA mismatches
  • To a lesser extent cleaves across a nick in dsDNA
  • Key enzyme for use in genome editing mutation detection workflows
  • Also available in convenient kit format: EnGen Mutation Detection Kit (NEB #E3321)
  • Need help finding the right exonuclease for your experiments? Try Exo Selector 
insect with claimed text over top
Catalog # Concentration Size List Price Your Price Quantity
M0302S 10,000 units/ml 250 units $77.00
M0302L 10,000 units/ml 1,250 units $308.00
Please enter a quantity for at least one size
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