NEB is a proud sponsor of high school BioBuilder teams. This year, we will donate reagents to support teams and have created this page to help you conveniently locate request forms, information on NEB products and helpful technical resources (including tips, troubleshooting guides and educational videos).

About the BioBuilderClub:
At BioBuilder, synthetic biology challenges are presented an accessible way, giving everyone a chance to experience authentic and meaningful scientific problem solving. The BioBuilderClub supports small teams of high school students and teachers who want to use out-of-classroom time to design, build and/or test synthetic living systems. With online and in person group meetings, the BioBuilderClub brings together a community of teachers, students and STEM professionals, and welcomes all participants, regardless of their access to molecular biology laboratory facilities. Team projects can focus on grand challenges for society (sustainable fuel, clean water, public health) or local issues (stinkbug infestations, smelly feet or "ready-light" birthday candles). BioBuilder is delighted to partner with NEB as we bring the fun of learning by doing to US high school biodesign teams. To learn more about BioBuilderClub, click here to download a brochure. If you have any questions, please contact

Request materials for BioBuilderClub

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NEB Technical Resources
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NEW ENGLAND BIOLABS®, NEB®, HF®, NEBUILDER®, NEBIOCALCULATOR® and NEBCUTTER® are registered trademarks of New England Biolabs, Inc.
BIOBRICK® is a registered trademark of the BioBrick Foundation
GIBSON ASSEMBLY® is a registered trademark of Synthetic Genomics, Inc.
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    NEB TV Episode 1

    On this episode of NEB TV, we’re talking about synthetic biology. What is synthetic biology, who’s using synthetic biology, and where can synthetic biology take us in the not-too-distant future?

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    Introduction to NEBuilder HiFi DNA Assembly

    Find out how NEBuilder® HiFi DNA Assembly can reliably join DNA fragments in a single tube, isothermal reaction, with advantages over NEB Gibson Assembly®.

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    Golden Gate Assembly Workflow

    Find out how Golden Gate Assembly can be used to quickly join multiple DNA fragments.

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    Primer Design and Fragment Assembly Using NEBuilder® HiFi DNA Assembly or Gibson Assembly® E5510 E5520

    Watch an interactive tutorial on primer design to see how simple it really is to clone with either NEBuilder HiFi DNA Assembly or the Gibson Assembly Cloning Kit.

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    Why is My Restriction Enzyme Not Cutting DNA?

    Not getting the cleavage you expected? Let an NEB scientist help you troubleshoot your reaction.

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    Overview of PCR Cloning

    PCR Cloning is an easy and reliable cloning method. The name is derived from the use of a DNA amplification step to generate the amplicon. Learn more about the benefits and disadvantages of PCR Cloning.