Vaccinia Capping System
recombinant NEBU 37 SAM

GMP-grade reagent also available. Learn more.

A full system for enzymatic capping based on the Vaccinia virus Capping Enzyme (VCE)

  • Adds 7-methylguanylate cap structures (Cap 0) to the 5′ end of RNA generated by in vitro transcription
  • Cap 0 is required for efficient translation of the RNA in eukaryotic systems
  • mRNA Cap 2´-O-Methyltransferase (NEB #M0366) is required to generate cap 1 structure that reduces cellular innate immune response when the RNA is used in vivo.
  • Isolated from a recombinant source
  • Tested for the absence of endonucleases, exonucleases, RNases
Catalog # Concentration Size List Price Your Price Quantity
M2080S 10,000 units/ml 400 units $140.00
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