Nucleoside Digestion Mix

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The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method to generate single nucleosides from DNA or RNA for quantitative analysis by liquid chromatography-mass spectrometry (LC-MS), eliminating the need for sequential multi-step, time-consuming digestion protocols.

  • Convenient one-step protocol
  • Digests both DNA and RNA to single nucleosides
  • Low-glycerol formulation significantly reduces glycerol-induced ion suppression during MS analysis

"I am very happy with the NEB Nucleoside Digestion Mix. Not only does it provide greater levels of digestion, but it allows me to degrade both DNA and RNA simultaneously."
– R.K., Assistant Professor, University of Pennsylvania

Ordering Information

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