NEB offers a number of endonucleases and exonucleases that cleave DNA.
Exonucleases catalyze the removal of nucleotides in either the 5’ to 3’ or the 3’ to 5’ direction from single or double stranded DNA. Endonucleases cleave DNA nonspecifically and can be used to generate blunt ends for ligation or to shorten duplex DNA.
Learn more about common applications and properties of exonucleases and endonucleases.
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