HomeFAQsWhat is the difference between DNA Gyrase (E. coli) (NEB #M7636), Topoisomerase I (E. coli) (NEB #M0301), and 9°N™ Reverse Gyrase (NEB #M0200)?
FAQ: What is the difference between DNA Gyrase (E. coli) (NEB #M7636), Topoisomerase I (E. coli) (NEB #M0301), and 9°N™ Reverse Gyrase (NEB #M0200)?
DNA Gyrase (E. coli) (NEB #M7636) introduces negative supercoils into relaxed closed circular dsDNA. Topoisomerase I (E. coli) (NEB #M0301) relaxes negatively supercoiled DNA. 9°N™ Reverse Gyrase (NEB #M0200) introduces positive supercoils into negatively supercoiled and relaxed closed circular dsDNA.
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