NEBinspired is a science blog designed to share inspirational stories about trends in the life sciences, lab tips to help you save time, and life lessons to reflect on. Browse our collection of science stories, or filter to find a topic that you are passionate about. From groundbreaking discoveries to sustainable lab techniques and helpful online tools that will aid your experimental design, we have something for everyone. And if you can’t find what you’re looking for, not to worry – simply send us a message about topics you would like to see covered.

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Overcoming challenges in FFPE DNA library prep

Posted on Wednesday, October 25, 2023 By Joanne Gibson, Ph.D.

Formalin-fixed paraffin-embedded (FFPE) samples hold invaluable genetic insights, yet library preparation is notoriously challenging. FFPE preservation processes damage DNA, resulting in low yields, non-uniform ends, and other issues. Our advanced enzymatic solutions tackle these challenges, enabling the full utilization of FFPE samples for genetic analysis.

Topic: Tips for the lab, What is Trending in Science

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photograph of a blue gloved hand holding a slide with a tissue sample and an out of focus microscope in the background

Superior error detection using Authenticase enhances assembled gene synthesis

Posted on Tuesday, September 5, 2023 By Joanne Gibson, Ph.D.

Gene synthesis often grapples with residual errors in DNA fragments, making traditional error detection methods labor-intensive and expensive. Authenticase™ employs structure-specific enzymes for proficient error correction. Paired with Q5® High-Fidelity DNA Polymerase, it enhances DNA quality and simplifies the synthesis workflow.

Topic: What is Trending in Science, Tips for the lab

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Eraser on end of pencil erasing from a lined page

Sequencing Technologies and Bioinformatics: From data to workflow improvements 

Posted on Friday, August 4, 2023 By Lydia Morrison, M.S.  & based on an interview with Brad Langhorst, Ph.D.

Bioinformatics and computational biology relate to the analysis, interpretation and application of the data collected through biological research. In this blog post, we explore bioinformatics applications to genetic sequencing and the ways proximity between molecular biologists and bioinformatic scientists accelerates progress, amplifying research and product development impacts.

Topic: Career advice, What is Trending in Science

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Blue DNA strand

Mutate with Confidence! Tips and tools for successful site-directed mutagenesis experiments

Posted on Monday, June 26, 2023 By Joanne Gibson, Ph.D.

Site-directed mutagenesis methodologies have evolved from complex and time-consuming multi-day workflows to more efficient and streamlined protocols. In this blog post, we have compiled tips, tools and valuable insights from our scientists to maximize your efficiency and ensure your success.

Topic: Tips for the lab

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Stylized image of double helix

Adding Capabilities to CRISPR-Cas-Based Biotechnology

Posted on Tuesday, May 30, 2023 By Nicole Kelesoglu

The Robb Lab at NEB collaborates with both academic and industry researchers in their mission of discovery, characterization, and application development efforts with CRISPR-Cas systems. It’s always galvanizing to look to the origin of CRISPR tools and consider how this scientific field has expanded into multiple substrate types and applications over time. While NEB produces many useful Cas nucleases to support research and development, the Robb Lab is always pursuing novel, distinctive properties – inspired by the abundance and diversity of Cas nucleases found in nature.

Topic: What is Trending in Science

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Adding capabilities to CRISPR Cas based biotechnology

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