Yes, the kit is compatible with a wide range of DNA types other than linear DNA, including:
- Oligonucleotides and short DNA fragments: Both single-stranded and double-stranded oligonucleotides can be recovered using this kit. Please refer to the Protocol for Oligonucleotide Cleanup Using the Monarch® Mag PCR & DNA Cleanup Kit (5 μg) (NEB #T4130).
- Circular DNA: Both single-stranded and double-stranded circular DNA can be purified using the Protocol for Standard PCR & DNA Cleanup in a Manual Workflow Using the Monarch Mag PCR & DNA Cleanup Kit (5 μg) (NEB #T4130).
- Large DNA fragments (>25 kb), including genomic DNA: These can be effectively purified using a Protocol for Genomic DNA (gDNA) Cleanup Using the Monarch® Mag PCR & DNA Cleanup Kit (5 μg) (NEB #T4130).
- RCA products: Rolling Circle Amplification (RCA) reactions typically yield a high concentration of DNA and can be purified using the Protocol for RCA Reaction Cleanup Using the Monarch® Mag PCR & DNA Cleanup Kit (5 μg) (NEB #T4130).
For best results, please use the appropriate protocol on our website tailored to your specific sample type.
