{title:`Meet the Team`,anchor:`TeamList`,placeholder:null,icon:{src:`/en-us/-/media/nebus/page-images/research-labs/menu-icons/research_icon_team.svg?rev=73efe93f0bba49709f657e78215ed5b0&hash=F698DC7DB644D50105D8C2F7E411E0DA`,alt:`Research_Icon_Team`},teamList:[{memberDescription:`Hong joined NEB in 2003 as a visiting scientist and later as a Postdoctoral Fellow and Research Scientist, focusing on the biochemistry and structures of restriction enzymes, Type IIS and nicking enzymes. Hong turned his attention to RNA capping in 2013 and went on to help modernized RNA capping assays and discover novel mRNA capping enzymes. Hong established his research group in 2020 and continues his passion and enthusiasm on mRNA capping research and technology development.
`,memberName:`S. Hong Chan`,memberTitle:`Senior Principal Investigator`,mediaSrc:`/en-us/-/media/nebus/page-images/research-labs/chan-lab/employees/siu-hong_chan.jpg?rev=a151bcd87f474373b62b74cd115f391f&hash=89B2F45E2C5E12AF13616E1386E67EAF`,memberEducation:`B.Sc. (Hons), The Chinese University of Hong Kong, Hong Kong, PRC, 1996
Ph.D., The Chinese University of Hong Kong, Hong Kong, PRC, 2000`,memberLink:{text:`linkedin.com/in/s-hong-chan`,url:`https://www.linkedin.com/in/s-hong-chan-0011b932/`,target:`_blank`}},{memberDescription:`

Daniel joined NEB in 2021 following a postdoctoral appointment with Andrey Kovalevsky at Oak Ridge National Laboratory using biophysics and structural biology to gain an atomistic understanding of viral enzyme drug targets. During his PhD training, he unraveled the diverse molecular mechanisms that drive drug-resistance evolution in HIV protease. In the Chan lab, Daniel is responsible for discovering enzymes to cap and modify mRNA. Daniel is revealing the detailed characteristics of new RNA modifying enzymes by combining creative bioinformatics with development of high-throughput analytical methods. By ensuring that the discovered enzymes integrate seamlessly into in vitro RNA synthesis technologies, he aims to expand access of important RNA modifications for the RNA and therapeutics scientific community.

`,memberName:`Daniel Kneller`,memberTitle:`Research Scientist I`,mediaSrc:`/en-us/-/media/nebus/page-images/research-labs/chan-lab/employees/daniel_kneller.jpg?rev=91d15d01c38c43518b14f9d861207abd&hash=EFD39D7711642AA220FF66F1C6E8FAF7`,memberEducation:`B.Sc., Bradley University, USA, 2012
Ph.D., Georgia State University, USA, 2019`,memberLink:{text:`linkedin.com/in/daniel-kneller`,url:`https://www.linkedin.com/in/daniel-kneller-phd/`,target:`_blank`}},{memberDescription:`

Christa joined NEB as a postdoctoral fellow in June 2022 following the completion of her Ph.D. at Boston University, where she studied ATPase enzyme kinetics and protein-protein interactions of the cytosolic iron-sulfur cluster assembly and trafficking (CIA) system under Dr. Deborah Perlstein. Here, Christa focused on elucidating the mechanism of the viral mRNA capping enzyme FCE. Christa later joined the lab as a Research Scientist in February 2024. In her new position, Christa continues to explore RNA 5′ modifying enzymes by utilizing her mechanistic expertise and pushing the enzymatic capabilities of these complex multi-functional enzymes. In her free time, Christa enjoys listening to podcasts, going on long walks, and checking out new breweries.

`,memberName:`Christa Molé`,memberTitle:`Research Scientist I`,mediaSrc:`/en-us/-/media/nebus/page-images/research-labs/chan-lab/employees/christa_mole.jpg?rev=42c44ef61ab349fcb6c294cbe31620df&sc_lang=en-us&hash=FD1EAAD5AFCAAB8897B932F8A2BE42DC`,memberEducation:`B.Sc., Quinnipiac University, USA, 2016
PhD., Boston University, USA, 2022`,memberLink:{text:`linkedin.com/in/christamole`,url:`https://www.linkedin.com/in/christamolez/`,target:`_blank`}}],moreLink:{text:`Meet the Team & Alumni`,url:`/en-us/research-labs/chan-lab/meet-the-team`,target:null}}

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