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Bringing more COVID-19 testing to Africa
Posted on Thursday, January 27, 2022 By
With so few Africans vaccinated against COVID-19, simple and sensitive tests are critical for saving lives. NEB is donating reagents to aid in the development of diagnostic tests (cLAMP) that can be used instead of PCR and can deliver rapid results detected by a simple color change. They are ideally suited for resource-poor areas by not requiring expensive laboratory equipment.
Proven tips for PCR primer design
Posted on Monday, November 8, 2021 By
PCR optimization and validation is a longtime passion at NEB. Avoid common PCR pitfalls and obtain the amplicon you desire with these primer design tips from our experts.
Using large-scale RNA sequencing to probe immune response, including autoimmune disease and vaccination
Posted on Wednesday, October 13, 2021 By
Researchers are efficiently exploring immune responses with a new bulk RNA sequencing workflow that generates full-length reads of B or T cell receptor V(D)J and (C) region mRNA. The discoveries incorporating this unique view are shedding light on previously unanswerable questions surrounding immune response to infection and therapeutic intervention.
8 tips to follow when choosing a restriction enzyme for in vitro mRNA vaccine production
Posted on Friday, September 24, 2021 By
mRNA vaccines have emerged as alternatives to conventional vaccine approaches because of the streamlined path from early discovery and development to a point-of-care therapeutic. In this post, read practical tips to consider when choosing a restriction enzyme for one of the crucial first steps of IVT vaccine development - linearizing the plasmid that contains the vaccine target sequence.
Bioinformatics alerts for viral variant impacts on molecular tests
Posted on Wednesday, August 11, 2021 By
NEB bioinformatics scientist Brad Langhorst, Ph.D., discusses the impact of emerging variants on existing SARS-CoV-2 molecular tests, the key factor in test failures, who benefits from using NEB's new, Primer Monitor tool, and lessons from the pandemic for infectious disease outbreaks.
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