RNA and rRNA Depletion Solutions from New England Biolabs®
Choose NEB® for your RNA depletion needs
Are abundant RNAs in your sample masking the biological significance of less abundant transcripts? NEBNext® offers several RNA depletion kits to support your research:
• Suitable for low-quality (e.g., FFPE) and high-quality RNA
• Compatible with a broad range of input amounts
• Streamlined workflow
• Customizable option to deplete unwanted RNA from any organism
Get more of
what you want
The NEBNext RNA depletion workflow utilizes targeted DNA probes and RNase H to selectively bind to and degrade abundant RNAs.
Abundant transcripts in your sample?
In this webinar we present advances in our method to eliminate cytoplasmic and mitochondrial ribosomal RNA from human, mouse, and rat total RNA samples.
View Webinar
NEBNext RNA Depletion Brochure
Learn more about the NEBNext kits for the removal of abundant, unwanted human, mouse, rat or bacterial RNAs in your sample. We also have a custom depletion kit if you are working with a different organism.
View Brochure
Directional rRNA Depletion
This technical note describes RNA library preparation using a rRNA depletion workflow and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina®.
Read Tech NoteFeatured RNA and rRNA depletion products
Discover NEBNext RNA depletion kits for precise removal of abundant RNA species in your samples. Our workflow utilizes targeted DNA probes and RNase H to selectively degrade unwanted RNAs, ensuring high-quality results. Choose from predesigned kits for bacteria, human, mouse, and rat samples, or choose a custom approach for another species, to streamline your research.
NEBNext rRNA Depletion Kit v2 (Human/Mouse/ Rat)
NEBNext rRNA Depletion Kit v2 (Human/Mouse/ Rat)
This kit is available with (NEB #E7405) and without (NEB #E7400) RNA Sample Purification Beads for the removal of human, mouse or rat ribosomal RNA upstream of next generation sequencing and other applications.
NEBNext rRNA Depletion Kit (Bacteria)
NEBNext rRNA Depletion Kit (Bacteria)
This kit is available with (NEB #E7860) or without (NEB #E7850) RNA Sample Purification Beads for the efficient and specific removal of bacterial ribosomal RNA.
NEBNext Globin & rRNA Depletion Kit (Human/ Mouse/Rat)
NEBNext Globin & rRNA Depletion Kit (Human/ Mouse/Rat)
This kit is available with (NEB #E7755) or without (NEB #E7750) RNA Sample Purification Beads for the removal of highly abundant globin mRNA and rRNA in blood samples.
NEBNext RNA Depletion Core Reagent Set
NEBNext RNA Depletion Core Reagent Set
This kit is available with (NEB #E7870) or without (NEB #E7865) RNA Sample Purification Beads for a customized approach to deplete unwanted RNA from any organism.
This content is covered by patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. For more information, please email us at gbd@neb.com. The use of these products may require you to obtain additional third party intellectual property rights for certain applications.
