New England Biolabs ships its products in plastic foam (polystyrene) containers with gel ice packs and recommends that its distributors do the same. Gel ice packs are kept at -20°C for at least 72 hours prior to shipment and the polystyrene boxes are tightly sealed. Tests have shown that products shipped under these conditions will stay at 2°C to 8°C for more than 24 hours. Testing at NEB has shown that there is no difference in activity and stability between enzymes that are shipped with gel ice packs and enzymes shipped on dry ice.
While New England Biolabs recommends storage of its enzymes at -20°C, exposure to higher temperatures (4 to 10°C) during shipping does not pose any risk to the enzymes. In fact, during the purification process (up to 3 weeks) enzymes are maintained at these temperatures as they are purified away from proteases and other contaminants which might interfere with their stability. Furthermore, each enzyme is shipped in a specific storage buffer which has been optimized for long-term stability.
NEB enzymes are stored in buffered 50% glycerol and remain liquid at temperatures down to -35°C. If these enzymes are shipped at colder temperatures (for example, in the presence of dry ice) the products will freeze. Proteins subjected to repeated freeze/thaw cycles may lose activity.
We have used these shipping conditions for the 40+ years that we have been providing DNA restriction and modifying enzymes and related products to the scientific community. If this shipping procedure posed any risk to our products, we would change the procedure immediately.
New England Biolabs offers free shipping to all U.S. available locations for all orders totaling $350.00 (net) and over.
U.S. orders under $350.00 are currently charged $29.00 per order for shipping and handling. Charges are prepaid and added to invoice.
Please inquire for international shipping charge quotation.
Orders received Monday through Thursday by 7:30 PM (EST) are shipped the same day for next business day delivery (within carrier's overnight delivery area)*. After 7:30 PM, but before 8:00PM (EST), please phone your order into Customer Service at 1-800-632-5227 (1-800-NEB-LABS), who can confirm if next business day delivery is still possible.
Orders placed by 7:30 PM (EST) on Friday will be shipped (with extra ice packs, as necessary) to NEB’s courier, who stores the products at the appropriate storage temperature, prior to Sunday shipment, for delivery the following Monday (or next business day) nationwide. This service is available for the same cost as our standard shipping service. Please note: Monday delivery service is not available for some products that have storage temperatures other than -20°C or require shipment on dry ice.
Please contact Customer Service at 1-800-NEB-LABS or email@example.com with any inquiries regarding NEB holiday deliveries or weather-related delays.
Shipping policies subject to change at any time.
*Shipments to Hawaii are not processed on Thursdays to avoid any delay resulting in a weekend delivery. Orders placed on a Thursday for shipment to Hawaii will be shipped on Friday for delivery on Monday. "Local" orders received Monday through Friday before 10:00 AM (EST) can be delivered the same day to most of the Boston and Cambridge area. Please contact Customer Service, 1-800-NEB-LABS or firstname.lastname@example.org to arrange for this special service at no extra charge.