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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1997 Cloning of the BssHII restriction-modification system in Escherichia coli: BssHII methyltransferase contains circularly permuted cytosine-5 methyltransferase motifs. Nucl.Acids Res. Xu, S.Y., Xiao, J.P., Posfai, J., Maunus, R., and Benner, J
1994 Construction of pSC101 derivatives with Camr and Tetr for selection or LacZ' for blue/white screening. BioTechniques Xu, S.Y., and Fomenkov, A.
1991 Cofactor requirements of BamHI mutant endonuclease E77K and its suppressor mutants. J.Bacteriol. Xu, S.Y., and Schildkraut, I.
1991 Isolation of BamHI variants with reduced cleavage activities. J.Biol.Chem. Xu, S.Y., and Schildkraut, I.
2007 Discovery of natural nicking endonucleases Nb.BsrDI and Nb.BtsI and engineering of top-strand nicking variants from BsrDI and BtsI. Nucl.Acids.Res. Xu, S.Y.,  Zhu, Z., Zhang, P., Chan, S.H., Samuelson, J., Xiao, J., Ingalls D.and Wilson, G.
2006 Simultaneous amplification and screening of whole plasmids using the T7 bacteriophage replisome. Nucl.Acids.Res. Xu, Y., Kim, H-J., Kays, A., Rice, J.and Kong, H.
2001 Engineering a Nicking Endonuclease N.AlwI by Domain Swapping Proc.Natl.Acad.Sci.USA Xu, Y., Lunnen, K.and Kong, H.
2018 Characterization of Natural Colibactin–Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening Biochemistry Xue, M
2016 Redox pathway sensing bile salts activates virulence gene expression in Vibrio cholerae. Mol Microbiol. Xue, Y., Tue, F., Shi, M., Wu, C.Q., Ren, G., Wang, X., Fang, W., Song, H. and Yang, M.
2012 Dual binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell Xuehua Zhong, X., Du, J., Bernatavichute, Y.V., Stroud, H., Feng, S., Caro, E., Vashisht, A.A., Chin, H.G., Terragni, J., Tu, A., Hetzel, J., Wohlschlegel, J.A., Pradhan, S., Patel, D.J. and Jacobsen, S.E.