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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2003 Purification and characterization of the beta-trefoil fold protein barley alpha-amylase/subtilisin inhibitor overexpressed in Escherichia coli Protein Expr. Purif. Bonsager, B.C., et al.
2003 Study of protein splicing and intein-mediated peptide bond cleavage under high-cell-density conditions. Biotechnol.Prog. Sharma, S., Zhang, A., Wang, H., Harcum, S.W.and Chong S.
2003 Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes Proc. Natl. Acad. Sci. USA Sinars, C.R., et al.
2003 The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation J. Biol. Chem. Zhang, Z., et al.
2003 Zinc Ion Effects on Individual Ssp DnaE Intein Splicing Steps: Regulating Pathway Progression. Biochemistry Nichols, N.M., Benner, J.S., Martin, D.D.and Evans, T.C.Jr.
2003 Visualization of coupled protein folding and binding in bacteria and purification of the heterodimeric complex. Proc.Natl.Acad.Sci.USA Wang, H.and Chong, S.
2003 REBASE Restriction enzymes and methyltransferases. Nucl.Acids Res. Roberts, R.J., Vincze, T., Posfai, J.and Macelis, D.
2003 Purification of recombinant proteins from E.coli by engineered inteins. Methods Mol.Biol. Xu, M.-Q.and Evans, T.C., Jr.
2003 Revised Escherichia coli selenocysteine insertion requirements determined by in vivo screening of combinatorial libraries of SECIS variants. Nucl.Acids Res. Sandman, K.E., Tardiff, D.F., Neely, L.A.and Noren, C.J.
2003 Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase Science Rak, A., et al.