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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1989 Site-directed mutagenesis of the EcoRV methylase for the study of the functional role of the conserved sequences in N6-adenine methylases J. Cell Biochem Barshevsky,T. and Benner J.S.
2005 Site-specific DNA-nicking mutants of the heterodimeric restriction endonuclease R.BbvCI. J.Mol.Biol. Heiter, D.F., Lunnen, K.D.and Wilson, G.G.
2004 Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation Bioorg. Med. Chem. Lett. Takeda, S.,et al.
2009 Site-specific covalent labeling of proteins inside live cells using small molecule probes Bioorg. Med. Chem. Chattopadhaya, S., et al.
2005 Site-specific immobilization of proteins in a microarray using intein-mediated protein splicing Bioorg. Med. Chem. Lett. Girish, A., et al.
2011 Site-specific protein labeling by intein-mediated protein ligation. Methods Mol.Biol. Ghosh, I., Considine, N., Maunus, E., Sun, L., Zhang, A., Buswell, J., Evans, T.C.Jr.and Xu, M.Q.
2015 Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation Nucleic Acids Res Zhang, G., Esteve, P.O., Chin, H.G., Terragni, J., Dai, N., Correa, I.R. Jr. and Pradhan, S.
2015 Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation Nucleic Acids Res Zhang G et al
2006 SmpB triggers GTP hydrolysis of elongation factor Tu on ribosome by compensating for the lack of codon-anticodon interaction during trans-translation initiation J. Biol. Chem. Shimizu, Y. and Ueda, T.
2018 Solid-phase enzyme catalysis of DNA end repair and 3' A-tailing reduces GC-bias in next-generation sequencing of human genomic DNA Sci. Rep Zhang, A., Li, S., Apone, L., Sun, X., Chen, L., Ettwiller, L.M., Langhorst, B.W., Noren, C.J., Xu, M.Q.