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Publications

We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2013 Increasing cleavage specificity and activity of restriction endonuclease KpnI Nucleic Acids Research Kommireddy Vasu, Easa Nagamalleswari, Mai Zahran, Petra Imhof, Shuang-yong Xu, Zhenyu Zhu, Siu-Hong Chan, Valakunja Nagaraja
2013 Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer Nucleic Acids Research Bhattacharyya, S., Yu, Y., Suzuki, M., Campbell, N., Mazdo, J., Vasanthakumar, A., et al. 5-hmC Detection & Analysis
2015 A database for DNA restriction and modification: enzymes, genes and genomes. Nucleic Acids Research Roberts, R.J., Vincze, T., Posfai, J., Macelis, D.
2016 Hydroxymethyluracil modifications enhance the flexibility and hydrophilicity of double-stranded DNA. Nucleic acids research Carson, S., Wilson, J., Aksimentiev, A., Weigele, P. R., & Wanunu, M.
2014 Structural basis for Klf4 recognition of methylated DNA Nucleic Acids Research Yiwei Liu, Yusuf Olatunde Olanrewaju, Yu Zheng, Hideharu Hashimoto, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng
2014 Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix Nucleic Acids Research Horton, J.R., Wang, H., Mabuchi, M.Y., Zhang, X., Roberts, R.J., Zheng, Y., Wilson, G.G., Cheng, X
2014 Type I restriction enzymes and their relatives Nucleic Acids Research Wil A. M. Loenen, David T. F. Dryden, Elisabeth A. Raleigh, Geoffrey G. Wilson
2014 Efficient DNA ligation in DNA–RNA hybrid helices by Chlorella virus DNA ligase Nucleic Acids Research Gregory J. S. Lohman, Yinhua Zhang, Alexander M. Zhelkovsky, Eric J. Cantor, Thomas C. Evans Jr.
2010 Chromatin particle spectrum analysis: a method for comparative chromatin structure analysis using paired-end mode next-generation DNA sequencing Nucleic Acids Research Kent, N.A., Adams, S., Moorhouse, A., and Paszkiewicz, K.
2012 Stucture and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Research Horton, J.R., Mabuchi, M., Cohen-Karni, D., Zhang, X., Griggs, R., Samaranayake, M., Roberts, R.J., Zheng, Y. and Cheng, X.