HomeFAQsMy SARS-CoV-2 sample or Internal Control reaction turned orange/yellow upon sample addition. Does that mean that the sample contains nucleic acid?
FAQ: My SARS-CoV-2 sample or Internal Control reaction turned orange/yellow upon sample addition. Does that mean that the sample contains nucleic acid?
A color change to yellow or orange upon the addition of sample nucleic acid for the internal control or SARS-CoV-2 test sample reactions indicates that the input material is incompatible with the assay and the results are invalid. It should not be interpreted to signify the presence of target nucleic acid. Repeat with a lower sample volume or adjust the sample input pH to ~ 8. If the NTC or PC reactions immediately turn yellow or orange upon setup, repeat assay setup.
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