HomeFAQsWhat is the difference between using Fpg and hOOG1?
FAQ: What is the difference between using Fpg and hOOG1?
hOGG1 cuts the bond 3' to the modified base. This leaves a nick and the modified base in the DNA substrate. Fpg has the same basic substrate specificity, but it cuts 5' and 3' to the modified base. The modified base floats away and the DNA is left with a gap where the modified base used to be.
You have been idle for more than 20 minutes, for your security you have been logged out. Please sign back in to continue your session.
Sign in to your NEB account
Any items placed in your cart as a guest will be lost upon sign in or leaving the site.