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SNAP-Capture products are non-magnetic or magnetic agarose beads coupled to a benzylguanine substrate, used to selectively capture and immobilize SNAP-tag® fusion proteins from solution. These beads have a high loading capacity for SNAP-tag fusion proteins and show very low non-specific absorption of proteins from a complex lysate, making them suitable for pull-down applications.

SNAP-tag® is a registered trademark of New England Biolabs, Inc.

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    Publications related to SNAP-Capture
    • Maffei, M., Morelli, C., Graham, E., Patriarca, S., Donzelli, L., Doleschall, B., de Castro, Reis, F., Nocchi, L., Chadick, C.H., Reymond, L., Correa, I.R., Jr., Johnsson, K., Hackett, J.A., Heppenstall, P.A (2019) A ligand based system for receptor specific delivery of proteins Sci Rep; 9(1), 19214.. PubMedID: 31844114, DOI: 10.1038/s41598-019-55797-1
    • Kufer S.K. et al. (2005) Covalent immobilization of recombinant fusion proteins with hAGT for single molecule force spectroscopy Eur Biophys J; 35, 72-78. PubMedID: 16160825
    • Tugulu S. et al. (2005) Protein-functionalized polymer brushes Biomacromolecules; 6, 1602-1607. PubMedID: 15877383
    • Kindermann M. et al. (2003) Covalent and selective immobilization of fusion proteins J Am Chem Soc; 125, 7810-7811 . PubMedID: 12822993
    • Huber W. et al. (2004) SPR-based interaction studies with small molecular weight ligands using hAGT fusion proteins Anal Biochem; 333, 280-288 . PubMedID: 15450803
    • Engin S. et al. (2010) Benzylguanine Thiol self-assembled monolayers for the immobilization of SNAP-tag proteins on microcontact-printed surface structures Langmuir; ASAP, PubMedID: 20369837
    • Jongsma M.A., Litjens R. H. (2006) Self-assembling protein arrays on DNA chips by auto-labeling fusion proteins with a single DNA address Proteomics; 6, 2650-2655 . PubMedID: 16596705
    • Sielaff I. et al. (2006) Protein function microarrays based on self-immobilizing and self-labeling fusion proteins Chembiochem; 7, 194-202. PubMedID: 16342318
    • Iversen L. et al. (2008) Templated protein assembly on micro-contact-printed surface patterns. Use of the SNAP-tag protein functionality Langmuir; May 17, PubMedID: 18484753
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Products and content are covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc (NEB). The use of trademark symbols does not necessarily indicate that the name is trademarked in the country where it is being read; it indicates where the content was originally developed. The use of this product may require the buyer to obtain additional third-party intellectual property rights for certain applications. For more information, please email busdev@neb.com.

This product is intended for research purposes only. This product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.