Home FAQs Do you recommend NEBNext UltraShear™ for high-sensitivity, low error rate DNA library preparation?

FAQ: Do you recommend NEBNext UltraShear™ for high-sensitivity, low error rate DNA library preparation?

Use of NEBNext UltraShear for fragmentation has been reported to result in high sensitivity and low error rate compared to other enzymatic fragmentation methods and mechanical shearing (e.g. Covaris®), upstream of DNA library preparation. However, we do not have internal data for this application.