FAQ: What is the difference between T5 Exonuclease (NEB #M0363) and T5 Exonuclease (NEB #M0663)?

T5 Exonuclease (NEB #M0663) is a His-tagged version of the discontinued T5 Exonuclease (NEB #M0363)..  The unit definition has been modified to align with the GMP-grade* version of the product. Product performance, protein concentration and reaction conditions remain the same.

*"GMP-grade" is a branding term NEB uses to describe reagents manufactured at NEB’s Rowley facility. The Rowley facility was designed to manufacture reagents under more rigorous infrastructure and process controls to achieve more stringent product specifications and customer requirements. Reagents manufactured at NEB’s Rowley facility are manufactured in compliance with ISO 9001 and ISO 13485 quality management system standards. However, at this time, NEB does not manufacture or sell products known as Active Pharmaceutical Ingredients (APIs), nor does NEB manufacture its products in compliance with all of the Current Good Manufacturing Practice regulations.