FAQ: Can I use purification methods other than Agencourt RNAClean XP Magnetic Beads?

While rRNA depleted samples can be purified by ethanol precipitation or using RNA column cleanups such as the Monarch RNA Cleanup Kit (NEB #T2030) we recommend using RNAClean XP beads. For use with other columns check the column specification for RNA size range to make sure any fragmented RNA will be retained during the cleanup.