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Donald G. Comb Honorary Lectureship

Don Comb founded New England Biolabs in the mid-1970’s, with the advancement of science and stewardship of the environment as its highest priorities. To honor his work, NEB has established the annual Donald G. Comb Honorary Lectureship series. The scientists chosen as the Donald G. Comb Honorary Lecturer must exemplify qualities valued by NEB:  a passion for science, broad collaboration, mentorship of the next generation, and an aim to make fundamental scientific discoveries and then apply that knowledge to broadly impact life science research.  
 
The inaugural lecture took place on Wednesday, November 20th at NEB Ipswich Campus. The lecture "Structure and dynamics of macromolecular complexes using cryo-EM” was be presented by Eva Nogales of the University of California, Berkeley.



Dr. Eva Nogales, is a pioneer in the application of cryogenic electron microscopy (Cryo-EM) to biological problems. Cryo-EM is a technique that bridges the gap between molecules and cells, allowing the study of the large protein complexes that operate in living cells. The new insights provided by Dr. Nogales’ work have provided a deeper understanding of the large molecular machines that power the “central dogma” of DNA replication, transcription to RNA, and translation to protein. These studies have enabled understanding of how these machines function and how they can fail; from how antibiotics block the cellular protein factory to how the DNA replication machinery can introduce mistakes that can result in cancer or other diseases. In the course of her career, she has engaged in numerous collaborations with academic, government and industry scientists, is well known for her energy and passion for her work and her mentorship to many in pursuing a scientific career. 

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