Techniques used for methylation detection and analysis require high quality control DNA for comparison to sample DNA. In vitro methylated DNA using a CpG methyltransferase gives us the opportunity to specifically generate positive control DNA for methylation studies. Alternatively, mammalian DNA can also be used for methylation studies like bisulfite conversion, methyl sensitive PCR (MSP), methyl-DNA immunoprecipitation (Me-DIP) or by methyl-CpG binding domain (MBD)-based capture techniques.
Products and content are covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc (NEB). The use of trademark symbols does not necessarily indicate that the name is trademarked in the country where it is being read; it indicates where the content was originally developed. The use of this product may require the buyer to obtain additional third-party intellectual property rights for certain applications. For more information, please email email@example.com.
This product is intended for research purposes only. This product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.
If all cells are created from the same genetic material, why are there so many different cell types? Listen to Sriharsa Pradhan, Senior Scientist, RNA Biology at NEB, as he describes how DNA is methylated and how this affects the path of reading the DNA code the same way an obstruction would derail a train off its tracks.