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The message is spreading.
NEB has everything you need for your RNA-related workflows.
NEBNext UltraShear® Long Read
Fast enzymatic gDNA fragmentation for long-read sequencing, tunable from 2 - 30 kb, while preserving methylation markers. Automation-friendly, broad inputs, boosts yield for ONT/PacBio, reliable, cost-effective.
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Q5®-XT Hot Start High-Fidelity 2X Master Mix
High‑fidelity (~280× Taq) polymerase enables fast amplification of diverse targets up to 20 kb, with a hot-start setup, short extension times, and a 62°C universal annealing protocol.
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EnClose™ Cell-free dbDNA™ Synthesis Kit
Fast, fermentation‑free enzymatic DNA manufacturing delivers high‑purity, backbone‑free dbDNA lacking bacterial sequences, simplifying regulation, improving safety, and supporting sensitive mRNA workflows.
Learn MoreReview NEB’s Latest Research
Feature Article
This article traces molecular cloning’s history and progress, highlighting how improved enzymes, assembly methods, and DNA design tools have advanced cloning efficiency, precision and applications.
Featured Video
The NEBaseChanger® Primer Design Tool Tutorial video will explain how to design primers for site-directed and multi-site mutagenesis using NEBaseChanger. This tool is ideal for NEB Q5® and NEBuilder® HiFi DNA Assembly applications.
Application Note
Discover how NEB scientists accelerate protein expression using NEBuilder® HiFi DNA Assembly and RCA, enabling rapid, cell-free synthesis and purification workflows—ideal for synthetic biology and screening.
Application Note
Read about the benefits and considerations of using a single, universal annealing temperature in PCR with various high-fidelity products.
Web Tool
The latest version of NEBaseChanger® is available to help design site-directed mutagenesis primers. Compatible with ambiguous bases, substitute based on amino acid position, batch upload for multiple primer sets and add mutations to primer tails.
New Publication
Explore NEB Expressions, featuring a precision medicine case study from discovery to targeted therapy, cell-free dbDNA synthesis, enzymatic solutions for circular RNA enrichment, conservation efforts in Costa Rica, RNA workflow products and the 2026 Passion in Science Awards.
Trending Topics
Featured Podcast
Interview with Dr. Craig Martin describing DuoTether™ technology development
Featured Podcast
Interview with Dr. Craig Martin describing DuoTether™ technology development
Dr. Craig Martin describes DuoTether™ technology developed by his lab, which improves RNA production efficiency and quality.
Featured Video
Function and application of type II S Restriction Enzymes
Featured Video
Function and application of type II S Restriction Enzymes
Learn about the functionality of Type IIS restriction enzymes and their role in molecular cloning, RNA therapeutics and vaccine development.
Featured Webinar
Streamlining DNA assembly to protein synthesis with rapid, cell-free workflows
Featured Webinar
Streamlining DNA assembly to protein synthesis with rapid, cell-free workflows
Learn a faster cell-free workflow that streamlines DNA-to-protein expression, integrating NEB tools for efficient design, assembly, amplification, and expression processes.
