In recent years, the discovery of new classes and modifications of RNA has ushered in a renaissance of RNA-focused research. Did you know that NEB offers a broad portfolio of reagents for the purification, quantitation, detection, synthesis and manipulation of RNA? Experience improved performance and increased yields, enabled by our expertise in enzymology.


Transform your nucleic acid purification experience with Monarch®

Quickly and easily extract up to 100 µg of high quality total RNA from multiple sample types – all with one kit!

  • Use with blood, cells, tissues and tough-to-lyse samples
  • Effectively purify total RNA of all sizes, including small RNA (<200 nt)
  • Efficiently remove genomic DNA, as our Monarch Total RNA Miniprep Kit includes gDNA Removal Columns and DNase I

Learn more and request a sample


Quickly and easily clean up and concentrate RNA after extraction or following a variety of enzymatic reactions, including DNase I treatment, in vitro transcription, and end modifications.

  • Obtain highly-pure RNA in minutes with no carryover contamination
  • Available in 3 different binding capacities:  10 μg, 50 μg and 500 μg
  • Elute in low volumes for highly concentrated RNA (T2030: ≥ 6 μl, T2040: ≥ 20 μl and T2050: ≥ 50 μl)

Learn more or request a free trial

Optimize your RT-qPCR with Luna®

Experience superior performance across a wide variety of sample types

  • Increased thermostability with our novel reverse transcriptase
  • Non-interfering visible tracking dye helps to eliminate pipetting errors

Try a sample and see how Luna outperforms the competition

Get even more from less with NEBNext® Ultra™ II Library Prep for RNA-seq

Generate high-quality libraries even with limited amounts of RNA

  • Save time with streamlined workflows, reduced hands-on time and automation compatibility
  • Order reagents specific to your needs, including directional and non-directional kits, rRNA depletion and poly(A) mRNA isolation
    reagents, and adaptors and primers (12- and 96-index) sold separately
  • Working with Small RNA? Minimize adaptor-dimer formation while achieving high yield, diverse multiplex libraries with our unique Small RNA library preparation workflow.

View performance data and request a free sample

Synthesize high-quality RNA with reagents designed to simplify your workflow

View full list of products for RNA synthesis





One or more of these products are covered by patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. For more information, please email us at gbd@neb.com. The use of these products may require you to obtain additional third party intellectual property rights for certain applications.

Get started with these RNA-related references:

RNA Synthesis Brochure
Learn more about NEB's products for synthesis of RNA, which range from template generation to poly(A) tailing.

Monarch Nucleic Acid Purification Brochure
It’s time to transform your DNA and RNA purification experience! Learn about the advantages of choosing Monarch Nucleic Acid Purification Kits from NEB.

Luna Universal qPCR And RT-qPCR Brochure
Make a simpler choice with Luna! Learn about the advantages of choosing Luna products for your qPCR & RT-qPCR, and see how Luna products compare to other commercially available reagents.

NEBNext for Illumina Brochure
Review NEB's extensive range of NGS sample prep products for RNA, Small RNA and DNA.

RNA Metro Map Poster
Download our RNA poster to learn more about the various RNA structures and recent applications.

RNA Technical Guide
Find in depth information on tools designed to streamline your RNA workflows, including RNA extraction & purification, qPCR and RT-qPCR, RNA-seq, RNA synthesis and gRNA synthesis.