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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2020 Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 A Nucleic Acids Research Horton, J.R., Yang, J., Zhang, X., Petronzio, T., Fomenkov, A., Wilson, G.G., Roberts, R.J., DasSarma, S
2005 Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI. Nucl.Acids.Res. Yang, Z., Horton, J.R., Maunus, R., Wilson, G.G., Roberts, R.R.and Cheng, X.
2015 Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA Nucleic Acids Res Hashimoto H et al
2015 Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA. Nucleic Acids Res Hashimoto H, Pais JE, Dai N, Corrêa IR Jr, Zhang X, Zheng Y, Cheng X.
1994 Structure of PvuII endonuclease with cognate DNA. EMBO J. Cheng, X., Balendiran, K., Schildkraut, I., and Anderson, J.E.
2003 Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase Science Rak, A., et al.
2016 Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities. PLoS Biol. Callahan, S.J., Luyten, Y.A., Gupta, Y.K., Wilson, G.G., Roberts, R.J., Morgan, R.D. and Aggarwal, A.K.
2013 Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA Nature Hashimoto, H., Pais, J.E., Zhang, X., Saleh, L., Qing Fu, Z., Dai, N., Correa, I.R. Jr., Zheng, Y. and Cheng X.
2014 Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA Nature Hashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ, Dai N, Corrêa IR Jr, Zheng Y, Cheng X
2014 Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA Nature Hashimoto H