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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2004 Structural characterization and comparative phylogenetic analysis of E.coli HemK, a protein (N5)-glutamine methyltransferase. Mol.Microbiol. Yang, Z., Shipman, L., Zhang, M., Anton, B., Roberts, R.J.and Cheng, X.
2012 Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering J Mol biol. Gupta, Y.K., Yang, L., Chan, S.H., Samuelson, J.C., Xu, S.-Y. and Aggarwal, A.K.
1990 Structural studies opf the BamHI restriction enzyme Biophys. J. Strzelecka, T., Dorner, L., Schildkraut, I., Aggarawal, A.
2001 Structural study of restriction enzyme MspI/DNA complex by x-ray crystallography Biophys. J. Xu, Q., O'Loughlin, T.J., Kucera, R.B., Schildkraut, I., Guo, H.-C.
2006 Structure and dynamics of the epidermal growth factor receptor C-terminal phosphorylation domain Protein Sci. Lee, N.Y., et al.
2000 Structure and function of the mouse DNA methyltransferase Gene, DNMT1 shows a tripartite structure. J.Mol.Biol. Margot, J.B., Aguirre-Arteta, A.M., DiGiacco, B.V., Pradhan, S., Roberts, R.J., Cardoso, M.C.and Leonhardt, H.
2014 Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI Sci Rep Horton JR, Nugent RL, Li A, Mabuchi MY, Fomenkov A, Cohen-Karni D, Griggs RM, Zhang X, Wilson GG, Zheng Y, Xu SY, Cheng X
2014 Structure of 5-hydroxymethylcytosine-specific restriction enzyme AbaSI in complex with DNA Nucleic Acids Res Horton JR, Borgaro JG, Griggs RM, Quimby A, Guan S, Zhang X, Wilson GG, Zheng Y, Zhu Z, Cheng X
1995 Structure of BamHI endonuclease bound to DNA: partial folding and unfolding on DNA binding. Science Newman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
1998 Structure of FokI has Implications for DNA Cleavage. Proc.Natl.Acad.Sci.USA Wah, D.A., Bitinaite, J., Schildkraut, I., Aggarwal, A.K.