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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2017 Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea J. Biol Chem. Heider, M.R., Burkhart, B.W., Santangelo, T.J., Gardner, A.F.
2017 Complete genome and methylome sequences of Salmonella enterica subsp. enterica Serovars Typhimurium, Saintpaul, and Stanleyville from the SARA/SARB collection Genome Announce Yao, K., Roberts, R.J., Allard, M.W., Hoffmann, M.
2017 DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target Nucl. Acids Res. Shen, B.W., Heiter, D.F., Lunnen, K.D., Wilson, G.G., Stoddard, B.L.
2017 DNA target recognition domains in the Type I restriction and modification systems of Staphylococcus aureus Nucl. Acids Res. Cooper, L.P., Roberts, G.A., White, J.H., Luyten, Y.A., Bower, E.K., Morgan, R.D., Roberts, R.J., Lindsay, J.A., Dryden, D.T.
2017 EcoBLMcrX, a classical modification-dependent restriction enzyme in Escherichia coli B: Characterization in vivo and in vitro with a new approach to cleavage site determination PLoS One Fomenkov, A., Sun, Z., Dila, D.K., Anton, B.P., Roberts, R.J., Raleigh, E.A.
2017 Caenorhabditis elegans CES-1 snail represses Pig-1 MELK expression to control asymmetric cell division. Genetics Wei, H., Yan, B., Gagneur, J., Conradt, B.
2017 High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding PNAS Evan A. Boyle, Johan O.L. Andreasson, Lauren M. Chircus, Samuel H. Sternberg, Michelle J. Wu, Chantal K. Guegler, Jennifer A. Doudna, and William J. Greenleaf
2017 Macrocycle peptides delineate locked-open inhibition mechanism for micoorganism phosphoglycerate mutases Nat. Commun. Yu, H., Dranchak, P., Li, Zhiru, MacArthur, R., Munson, M.S., Mehzabeen, N., Baird, N.J., Battalie, K.P., Ross, D., Lovell, Sc., Carlow, C.K.S., Suga, H., Inglese, J.
2017 Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA Nucleic Acids Res. Tamulaitiene, G., Jovaisaite, V., Tamulaitis, G., Songailiene, I., Manakova, E., Zaremba, M., Grazulis, S., Xu, S.Y., Siksnys, V.
2017 Methods for structural and functional analyses of intramembrane prenyltransferases in the UbiA superfamily Methods Enzymol Yang, Y., Ke, N., Liu, S., Li, W.