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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1994 Structure of PvuII endonuclease with cognate DNA. EMBO J. Cheng, X., Balendiran, K., Schildkraut, I., and Anderson, J.E.
1994 REBASE - restriction enzymes and methylases Nucl.Acids.Res. Roberts, R.J.and Macelis, D.
1994 Protein splicing: an analysis of the branched intermediate and its resolution by succinimide formation. EMBO J. Xu, M.Q., Comb, D.G., Paulus, H., Noren, C.J., Shao, Y., and Perler, F.B.
1994 Organization and sequence of the HpaII restriction-modification system and adjacent genes. Gene Kulakauskas, S., Barsomian, J.M., Lubys, A., Roberts, R.J., and Wilson, G.G.
1994 Ligand-induced conformational states of the cytosine-specific DNA methyltransferase M.HgaI-2. J.Mol.Biol. Baldwin, G.S., Kelly, S.M., Price, N.C., Wilson, G.G., Connolly, B.A., Artymiuk, P.J., and Hornby, D.P.
1994 Hhal Methyltransferase Flips its Target Base Out of the DNA Helix. Cell Klimasauskas, S., Kumar, S., Roberts, R.J., and Cheng, X.
1994 Restriction and modification. In: Molecular Biology of Bacteriophage T4 American Society for Microbiology, Washington, D.C. Carlson, K., Raleigh, E.A. and Hattman, S.
1994 An amazing distortion in DNA induced by a methyltransferase (Nobel lecture) Angew.Chem.Int.Ed.Engl. Roberts, R.J.
1994 An analysis of the humoral immune response of dogs following vaccination with irradiated infective larvae of Dirofilaria immitis. Parasite Immunol. Mejia, J.S., and Carlow, C.K.S.
1994 Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionine. Proc.Natl.Acad.Sci.USA Labahn, J., Granzin, J., Schluckebier, G., Robinson, D.P., Jack, W.E., Schildkraut, I., and Saenger, W.