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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2019 Fusion to Tetrahymena thermophila granule lattice protein 1 confers solubility to sexual stage malaria antigens in Escherichia coli. Protein Expression and Purification Agrawal, A., Bisharyan, Y., Papoyan, A, Bednenko, J., Cardarelli, J., Yao, M., Clark, T., Berkm​en, M., Ke, N., Colussi, P. Protein Expression,Protein Expression in E. Coli,Expression of Difficult Proteins,T7 Expression,Non-T7 Expression,Disulfide-bonded Protein Expression,Target Protein Insolubility
2019 Characterization of the internal translation initiation region in monoclonal antibodies expressed in Escherichia coli Journal of Biological Chemistry Leith, E.M., O'Dell, W.B., Ke, N., McClung, C., Berkmen, M., Bergonzo, C., Brinson, R.G., Kelman, Z Protein Analysis & Tools,Protein Expression,Proteomics,Protein Expression in E. Coli,Expression of Difficult Proteins,T7 Expression,Disulfide-bonded Protein Expression
Disulfide Bond Formation in the Periplasm of Escherichia coli EcoSal Plus Manta, Bruno; Berkmen, Mehmet; Protein Expression,Protein Expression in E. Coli,Expression of Difficult Proteins,Non-T7 Expression,Disulfide-bonded Protein Expression
2012 Production of disulfide-bonded proteins in Escherichia coli Protein Expression and Purification Berkmen, M. Protein Expression,Expression of Difficult Proteins,Disulfide-bonded Protein Expression
2010 In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling. Mol.Microbiol. Shouldice, S.R., Cho, S.H., Boyd, D., Heras, B., Eser, M., Beckwith, J., Riggs, P., Martin, J.L.and Berkmen, M. Protein Expression,Protein Expression in E. Coli,Expression of Difficult Proteins,Non-T7 Expression,Disulfide-bonded Protein Expression
2015 Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria Nature Communications Robinson, M.-P., Ke, N., Lobstein, J., Peterson, C., Szkodny, A., Mansell, T.J., Tuckey, C., Riggs, P.D., Colussi, P.A., Noren, C.J., Taron, C.H., Delisa, M.P., Berkmen, M. Protein Expression,Protein Expression in E. Coli,Expression of Difficult Proteins,T7 Expression,Disulfide-bonded Protein Expression
2015 Converting a Sulfenic Acid Reductase into a Disulfide Bond Isomerase Antioxidant and Redox Signaling Chatelle C, Kraemer S, Ren G, Chmura H, Marechal N, Boyd D, Roggemans C, Ke N, Riggs P, Bardwell J, Berkmen M Protein Expression,Expression of Difficult Proteins,Disulfide-bonded Protein Expression
2018 Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli. mAbs Mabs Reddy, P.T., Brinson, R.G., Hoopes, J.T., McClung, C., Ke, N., Kashi, L. Protein Expression,Protein Expression in E. Coli,Expression of Difficult Proteins,T7 Expression,Disulfide-bonded Protein Expression
2009 Comprehensive mapping of long range interactions reveals folding principles of the human genome Science Lieberman-Aiden E., van Berkum N., Williams L., Imakaev M., Ragoczy T., Telling A., Amit I., Lajoie B., Sabo P., Dorschner M., Sandstrom R., Bernstein B., BenderM. A., Groudine M., Gnirke A., Stamatoyannopoulos J., Mirny L., Lander E., Dekker J. Epigenetics
2014 Myogenic differential methylation: diverse associations with chromatin structure Biology (Basel) Chandra S, Baribault C, Lacey M, Ehrlich M Epigenetics