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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2011 Hypomethylation of a LINE-1 Promoter Activates an Alternate Transcript of the MET Oncogene in Bladders with Cancer PLoS Genet. Wolff, E.M. et al. Epigenetics
2016 Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction Nature Biotechnology Mooijman D, Dey S S, Boisset JC, Crosetto N, van Oudenaarden A Epigenetics
2016 Genetics: profiling DNA methylation and beyond Nature Methods Marx V. Epigenetics,Restriction Enzymes for Epigenetics
2015 TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy. J Clin Invest Zheng Hu, Wencheng Ding, Da Zhu, Lan Yu, Xiaohui Jiang, Xiaoli Wang, Changlin Zhang, Liming Wang, Teng Ji, Dan Liu, Dan He, Xi Xia, Tao Zhu, Juncheng Wei, Peng Wu, Changyu Wang, Ling Xi, Qinglei Gao, Gang Chen, Rong Liu, Kezhen Li, Shuang Li, Shixuan Wang, Jianfeng Zhou, Ding Ma, Hui Wang Genome Editing
2014 Enhanced gene disruption by programmable nucleases delivered by a minicircle vector. Gene Ther A-Bk Dad, S Ramakrishna, M Song, H Kim Genome Editing
2013 Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems Nucleic Acids Res DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM Gibson Assembly®
2013 Rapid, modular and reliable construction of complex mammalian gene circuits Nucleic Acids Res Guye P, Li Y, Wroblewska L, Duportet X, Weiss R Gibson Assembly®
2013 Identification of new proteins that modulate the germination of spores of bacillus species J Bacteriol Ramirez-Peralta A, Gupta S, Butzin XY, Setlow B, Korza G, Leyva-Vazquez MA, Christie G, Setlow P Gibson Assembly®
2013 A membrane-bound NAC transcription factor, ANAC017, mediates mitochondrial retrograde signaling in Arabidopsis Plant Cell Ng S, Ivanova A, Duncan O, Law SR, Van Aken O, De Clercq I, Wang Y, Carrie C, Xu L, Kmiec B, Walker H, Van Breusegem F, Whelan J, Giraud E Gibson Assembly®
2013 The oil palm SHELL gene controls oil yield and encodes a homologue of SEEDSTICK Nature Singh R, Low ET, Ooi LC, Ong-Abdullah M, Ting NC, Nagappan J, Nookiah R, Amiruddin MD, Rosli R, Manaf MA, Chan KL, Halim MA, Azizi N, Lakey N, Smith SW, Budiman MA, Hogan M, Bacher B, Van Brunt A, Wang C, Ordway JM, Sambanthamurthi R, Martienssen RA Gibson Assembly®