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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2004 Changing the Enzymatic Activity of T7 Endonuclease by Mutations at the Beta-Bridge Site: Alteration of Substrate Specificity Profile and Metal Ion Requirements by Mutation Distant from the Catalytic Domain. Biochemistry Guan, C., Kumar, S., Kucera, R.and Ewel, A.
2004 Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with Chromomethylase3. EMBO J. Lindroth, A.M., Shultis, D., Jasencakova, Z., Fuchs, J., Johnson, L., Scubert, D., Patnaik, D., Pradhan, S., Goodrich, J., Schubert, Il, Jenuwein, T., Khorasanizadeh, S.and Jacobsen, S.E
2004 Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans. Microbiology Grimme, S.J., Colussi, P.A., Taron,C.H.and Orlean, P.
2004 Engineering Strand-specific DNA Nicking Enzymes fro the Type IIS Restriction Endonucleases BsaI, BsmBI and BsmAI. J.Mol.Biol. Zhu, Z., Samuelson, J.C., Zhou, J., Dore, A.and Xu, S.-Y.
2004 Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans. Dev.Biol. Gissendanner, C.R., Crossgrove, K., Kraus, K.A., Maina, C.V.and Sluder, A.E.
2004 First sequenced genome of a parasitic nematode. Trends Parasitol. Ghedin, E., Wang, S., Foster, J.and Slatko, B.
2004 Helicase-dependent isothermaol DNA amplification EMBO Rep. Vincent, M., Xu, Y.and Kong, H.
2004 Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo. J.Biol.Chem. Taron, B.W., Colussi, P.A., Wiedman, J.M., Orlean, P.and Taron, C.H.
2004 Versatile protein biotinylation strategies for potential high-throughput proteomics J Am. Chem. Soc. Lue, R.Y., et al.
2004 Transposon-mediated linker insertion scanning mutagenesis of the Escherichia coli McrA endonuclease. J.Bacteriol. Anton, B.P.and Raleigh, E.A.