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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2003 Purification and characterization of the beta-trefoil fold protein barley alpha-amylase/subtilisin inhibitor overexpressed in Escherichia coli Protein Expr. Purif. Bonsager, B.C., et al.
2003 Directed evolution of O6-alkylguanine-DNA alkyltransferase for efficient labeling of fusion proteins with small molecules in vivo Chem. Biol.  Juillerat A. et al.
2003 Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein RNA Zuberek, J., et al.
2003 Protein trans-splicing in transgenic plant chloroplast: Reconstruction of herbicide resistance from split genes. Proc.Natl.Acad.Sci.USA Chin, H.G., Kim, G.D., Marin, I., Mersha, F., Evans, T.C.Jr., Chen, L., Xu, M.-Q.and Pradhan, S.
2003 Crystallization of restriction endonuclease SfiI in complex with DNA Acta Crystallogr. D Biol. Crystallogr. Viadiu, H., Vanamee, E.S., Jacobson, E.M., Schildkraut, I. and Aggarawl, A.K.
2003 Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J.Biol.Chem. Ding, Y., Xu, M.-Q., Ghosh, I., Chen, X., Ferrandon, S., Lesage, G., Rao, Z.
2003 Generation of the R2 subunit of ribonucleotide reductase by intein chemistry: insertion of 3-nitrotyrosine at residue 356 as a probe of the radical initiation process Biochemistry Yee, C.S., et al.
2003 Glucocorticoid Receptor-like Zn(Cys)4 Motifs in Bsl I Restriction Endonuclease. J.Mol.Biol. Vanamee, E.S., Hsieh, P.C., Zhu, Z., Yates, D., Garman, E., Xu, S.Y.and Aggarwal, A.K.
2003 Semisynthesis and application of carboxyfluorescein-labelled biologically active human interleukin-8 Biol. Chem. David, R., et al.
2003 Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes Proc. Natl. Acad. Sci. USA Sinars, C.R., et al.