We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.
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|2011||A type IV modification-dependent restriction enzyme SauUSI from Staphylococcus aureus subsp.aureus USA300.||Nucl.Acids.Res.||Xu, S.Y., Corvaglia, A.R., Chan, S.H., Zheng, Y.and Linder, P.|
|2016||Expression and purification of the modification-dependent restriction enzyme BisI and its homologous enzymes||Sci Rep||Xu, S.Y., Klein, P., Degtyarev, S.K.h. and Roberts, R.J.|
|2011||Characterization of Type II and III restriction modification systems from Bacillus cereus strains||J. Bacteriol.||Xu, S.Y., Nugent, R.L., Kasamkattil, J., Fomenkov, A., Gupta, Y., Aggarwal, A., Wang, X., Li, Z., Zheng, Y. and Morgan, R.|
|2012||Characterization of Type II and III restriction-modification systems from Bacillus cereus strains ATCC10987 and ATCC14579.||J.Bacteriol.||Xu, S.Y., Nugent, R.L., Kasamkattil, J., Fomenkov, A., Gupta, Y., Aggarwal, A., Wang, X., Li, Z., Zheng, Y.and Morgan, R.|
|1998||Cloning and expression of the ApaLI, NspI, NspHI, SacI, ScaI and SapI restriction-modification systems in Escherichia coli||Mol.Gen.Genet.||Xu, S.Y., Xiao, Ettwiller L., holden, M., Aliotta, J., Poh, C.L., Dalton, M., Robinson, D.P., Petronzio, T.R., Moran, L., Ganatra, M., Ware, J., Slatko, B.and Benner, J.|
|1997||Cloning of the BssHII restriction-modification system in Escherichia coli: BssHII methyltransferase contains circularly permuted cytosine-5 methyltransferase motifs.||Nucl.Acids Res.||Xu, S.Y., Xiao, J.P., Posfai, J., Maunus, R., and Benner, J|
|1994||Construction of pSC101 derivatives with Camr and Tetr for selection or LacZ' for blue/white screening.||BioTechniques||Xu, S.Y., and Fomenkov, A.|
|1991||Cofactor requirements of BamHI mutant endonuclease E77K and its suppressor mutants.||J.Bacteriol.||Xu, S.Y., and Schildkraut, I.|
|1991||Isolation of BamHI variants with reduced cleavage activities.||J.Biol.Chem.||Xu, S.Y., and Schildkraut, I.|
|2007||Discovery of natural nicking endonucleases Nb.BsrDI and Nb.BtsI and engineering of top-strand nicking variants from BsrDI and BtsI.||Nucl.Acids.Res.||Xu, S.Y., Zhu, Z., Zhang, P., Chan, S.H., Samuelson, J., Xiao, J., Ingalls D.and Wilson, G.|