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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1999 InBase, the New England Biolabs Intein Database. Nuc.Acids Res. Perler, F.B.
1999 KDR Activation in Astrocytic Neoplasms. Cancer Carroll, R.S., Zhang, J., Bello, L., Melnick, M.B., Maruyama, T.and Black, P.M.
1999 Mutations of endo-B-N-acetylglucosaminidase H active site residues Asp130 and Glu132: Activities and conformations. Protein Sci. Rao, V., Cui, T., Guan, C., and Van Roey, P.
1999 A Mutant of BamHI Restriction Endonuclease which Requires N6-Methyladenine for Cleavage. J.Mol.Biol. Whitaker, R.D., Dorner, L.F.and Schildkraut, I.
1999 Purification of Proteins Fused to Either the Amino or Carboxy Terminus of the Mycobacterium xenopi Gyrase A Intein. Cloning and Expression vectors for Gene Function Analysis Southworth, M.W., Amaya, K., Evans, T.C., Xu, M.Q.and Perler, F.B.
1999 Protein-Modulated DNA Electron Transfer. J.Am.Chem.Soc. Rajski, S.R., Kumar, S., Roberts, R.J.and Barton, J.K.
1999 REBASE-restriction enzymes and methylases. Nucl.Acids Res. Roberts, R.J.and Macelis, D.
1999 Recombinant Human DNA (Cytosine-5) Methyltransferase.I.expression, purification, and comparison of de novo and maintenance. J.Biol.Chem. Pradhan, S., Bacolla, A., Wells, R.D.and Roberts, R.J.
1999 The Cyclization and Polymerization of Bacterially Expressed Proteins Using Modified Self-splicing Inteins. J.Biol.Chem. Evans, T.C., Benner, J.and Xu, M-Q
1999 Structural Insights into the Mechanism of Intramolecular Proteolysis. Cell Xu, M.Q., Buckley, D., Guan, C.and Guo, H-C