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Publications

We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2014 Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks Nucleic Acids Res Singh A, Minia I, Droll D, Fadda A, Clayton C, Erben E
2014 Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes J Cell Sci Arakel EC, Brandenburg S, Uchida K, Zhang H, Lin YW, Kohl T, Schrul B, Sulkin MS, Efimov IR, Nichols CG, Lehnart SE, Schwappach B Glycobiology
2014 The Serine-Threonine Protein Kinase PAK4 Is Dispensable in Zebrafish: Identification of a Morpholino-Generated Pseudophenotype PLoS One Law SH, Sargent TD Gibson Assembly®
2014 The other face of restriction: modification-dependent enzymes. Nucleic Acids Res Loenen, W.A., Raleigh, E.A. Restriction Enzyme Digestion,Restriction Enzyme Digestion
2014 The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense Oncogene Itahana Y, Han R, Barbier S, Lei Z, Rozen S, Itahana K Glycobiology
2014 Therapeutic epitopes of Leptospira LipL32 protein and their characteristics Protein Eng Des Sel Maneewatch S, Adisakwattana P, Chaisri U, Saengjaruk P, Srimanote P, Thanongsaksrikul J, Sakolvaree Y, Poungpan P, Chaicumpa W Phage Display
2014 Time-resolved fluorescence of 2-aminopurine in DNA duplexes in the presence of the EcoP15I Type III restriction-modification enzyme Biochem Biophys Res Commun Ma L, Wu X, Wilson GG, Jones AC, Dryden DT
2014 Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence Genes Dev Hashimoto H, Olanrewaju YO, Zheng Y, Wilson GG, Zhang X, Cheng X
2014 Whole-genome haplotyping using long reads and statistical methods. Nature Biotechnology Kuleshov, K. et al.
2014 REBASE - A database for DNA restriction and modification: enzymes, genes and genomes Nucleic Acids Research, Advance Access Roberts, R.J., Vincze, T., Posfai, J., Macelis, D.
2014 Wolbachia endosymbionts and human disease control Mol. Biochem. Parasitol. Slatko, B. E., Luck, A. N., Dobson, S. L. and Foster, J. M.
2014 Type II Cadherins Guide Assembly of a Direction-Selective Retinal Circuit. Cell Xin Duan, Arjun Krishnaswamy, Irina De la Huerta, Joshua R Sanes High-Fidelity PCR
2014 Type I restriction enzymes and their relatives Nucleic Acids Research Wil A. M. Loenen, David T. F. Dryden, Elisabeth A. Raleigh, Geoffrey G. Wilson
2014 Type II restriction endonucleases-a historical perspective and more Nucleic Acids Res Pingoud A, Wilson GG, Wende W
2014 Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering Sci Rep Horii T, Arai Y, Yamazaki M, Morita S, Kimura M, Itoh M, Abe Y, Hatada I Gibson Assembly®
2014 Ubiquity and diversity of human-associated demodex mites. PLoS One Megan S Thoemmes, Daniel J Fergus, Julie Urban, Michelle Trautwein, Robert R Dunn Routine PCR
2014 Co-evolution between an Endosymbiont and Its Nematode Host: Wolbachia Asymmetric Posterior Localization and AP Polarity Establishment PLoS Negl Trop Dis Landmann F, Foster JM, Michalski ML, Slatko BE, Sullivan W
2014 Clathrin-independent pathways do not contribute significantly to endocytic flux Elife Bitsikas V, Corrêa IR, Nichols BJ
2014 Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression BMC Genomics Luck, A.N., Evans, C.C., Foster, J.M., et al.
2014 Comparison of Subtypes of Listeria monocytogenes Isolates from Naturally Contaminated Watershed Samples with and without a Selective Secondary Enrichment PLoS ONE Gorski L, Walker S, Liang AS, Nguyen KM, Govoni J, et al.
2014 Characterization of Family D DNA polymerase from Thermococcus sp. 9°N Extremophiles Greenough L, Menin JF, Desai NS, Kelman Z, Gardner AF
2014 Identification and characterization of mutant clones with enhanced propagation rates from phage-displayed peptide libraries Anal Biochem Nguyen KT, Adamkiewicz MA, Hebert LE, Zygiel EM, Boyle HR, Martone CM, Meléndez-Ríos CB, Noren KA, Noren CJ, Hall MF
2014 Cofactor-Independent Phosphoglycerate Mutase from Nematodes Has Limited Druggability, as Revealed by Two High-Throughput Screens PLoS Negl Trop Dis. Crowther, G.J., Booker, M.L., He, M., Li, T., Raverdy, S., Novelli, J.F., He, P., Dale, N.R.G., Fife, A.M., Barker, R.H., Jr., Kramer, M.L., Van Voorhis, W.C., Carlow, C.K.S. and Wang, M-W.
2014 Consequences of the disease-related L78R mutation for dimerization and activity of STAT3 J Cell Sci Domoszlai T, Martincuks A, Fahrenkamp D, Schmitz-Van de Leur H, Küster A, Müller-Newen G Cellular Analysis,SNAP Cell
2014 Identification and Characterization of a Suite of Tumor Targeting Peptides for Non-Small Cell Lung Cancer Sci Rep McGuire MJ, Gray BP, Li S, Cupka D, Byers LA, Wu L, Rezaie S, Liu YH, Pattisapu N, Issac J, Oyama T, Diao L, Heymach JV, Xie XJ, Minna JD, Brown KC Phage Display
2014 Identification and characterization of mutant clones with enhanced propagation rates from phage-displayed peptide libraries Anal Biochem Nguyen KT, Adamkiewicz MA, Hebert LE, Zygiel EM, Boyle HR, Martone CM, Meléndez-Ríos CB, Noren KA, Noren CJ, Hall MF Phage Display
2014 Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom J Bacteriol Phelan VV, Moree WJ, Aguilar J, Cornett DS, Koumoutsi A, Noble SM, Pogliano K, Guerrero CA, Dorrestein PC Gibson Assembly®
2014 Identification of restriction-modification systems of Bifidobacterium animalis subsp. lactis CNCM I-2494 by SMRT sequencing and associated methylome analysis PLoS One O'Connell Motherway M, Watson D, Bottacini F, Clark TA, Roberts RJ, Korlach J, Garault P, Chervaux C, van Hylckama Vlieg JE, Smokvina T, van Sinderen D
2014 Highlights of the DNA cutters: a short history of the restriction enzymes Nucleic Acids Res Loenen WA, Dryden DT, Raleigh EA, Wilson GG, Murray NE
2014 Genomics of CpG methylation in developing and developed zebrafish G3 (Bethesda) McGaughey DM, Abaan HO, Miller RM, Kropp PA, Brody LC
2014 Identification and Characterization of a Proteolytically Primed Form of the Murine Coronavirus Spike Proteins after Fusion with the Target Cell J Virol Wicht O, Burkard C, de Haan CA, van Kuppeveld FJ, Rottier PJ, Bosch BJ Glycobiology
2014 Identification and Biosynthesis of a Novel Xanthomonadin-Dialkylresorcinol-Hybrid from Azoarcus sp. BH72 PLoS One Schöner TA, Fuchs SW, Reinhold-Hurek B, Bode HB Gibson Assembly®
2014 Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science Jaitin, DA., Kenigsberg, E., Keren-Shaul, H., Elefant, N., Paul, F., Zaretsky, I., Mildner, A., Cohen, N., Jung, S., Tanay, A. and Amit, I.
2014 Loop-mediated isothermal amplification for detection of nucleic acids Curr Protoc Mol Biol Tanner NA, Evans TC Jr. Isothermal Amplification
2014 MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress Epigenetics Laget S, Miotto B, Chin HG, Estève PO, Roberts RJ, Pradhan S, Defossez PA
2014 Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation J Biol Chem Estève PO, Terragni J, Deepti K, Chin HG, Dai N, Espejo A, Corrêa IR Jr, Bedford MT, Pradhan S
2014 Mediated enrichment of siRNAs Methods in Molecular Biology Jin J., McReynolds L.A. and Gullerova M.
2014 Insights into the initiation of JC virus DNA replication derived from the crystal structure of the T-antigen origin binding domain PLoS Pathog Meinke G, Phelan PJ, Kalekar R, Shin J, Archambault J, Bohm A, Bullock PA Gibson Assembly®
2014 Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16 AMB Express Gai CS, Lu J, Brigham CJ, Bernardi AC, Sinskey AJ Gibson Assembly®
2014 Integration of growth and patterning during vascular tissue formation in Arabidopsis Science Bert De Rybel, Milad Adibi, Alice S. Breda, Jos R. Wendrich, Margot E. Smit, Ondej Novk, Nobutoshi Yamaguchi, Saiko Yoshida, Gert Van Isterdael, Joakim Palovaara, Bart Nijsse, Mark V. Boekschoten, Guido Hooiveld, Tom Beeckman, Doris Wagner, Karin Ljung, Christian Fleck, Dolf Weijers High-Fidelity PCR
2014 Live-cell reporters for fluorescence imaging Curr Opin Chem Biol Corrêa IR Jr.
2014 Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity Sci Rep Phua KK, Staats HF, Leong KW, Nair SK
2014 Engineering hydrogen gas production from formate in a hyperthermophile by heterologous production of an 18-subunit membrane-bound complex J Biol Chem Lipscomb GL, Schut GJ, Thorgersen MP, Nixon WJ, Kelly RM, Adams MW Gibson Assembly®
2014 Engineering Bacterial Transcription Regulation To Create a Synthetic in Vitro Two-Hybrid System for Protein Interaction Assays J Am Chem Soc Zhou Y, Asahara H, Schneider N, Dranchak P, Inglese J, Chong S
2014 Engineering nicking enzymes that preferentially nick 5-methylcytosine-modified DNA Nucleic Acids Res Gutjahr A, Xu SY Gibson Assembly®
2014 Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells PLoS One Fröhlich LF, Mrakovcic M, Smole C, Lahiri P, Zatloukal K
2014 Enhanced gene disruption by programmable nucleases delivered by a minicircle vector. Gene Ther A-Bk Dad, S Ramakrishna, M Song, H Kim Genome Editing
2014 DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase BMC Microbiol Kaur K, Taneja NK, Dhingra S, Tyagi JS Phage Display
2014 Development of VHH Antibodies against Dengue Virus Type 2 NS1 and Comparison with Monoclonal Antibodies for Use in Immunological Diagnosis PLoS One Fatima A, Wang H, Kang K, Xia L, Wang Y, Ye W, Wang J, Wang X. Phage Display
2014 Diversity and Expression of MicroRNAs in the Filarial Parasite, Brugia malayi. PLoS One Poole CB, Gu W, Kumar S, Jin J, Davis PJ, Bauche D, McReynolds LA.