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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1989 Isolation and characterization of restriction endonuclease BstFI and BstSI from Bacillus stearothermophilus. J.Fudan Univ.Natural Sci. Chen Z., Kong, H.and Wang, L.
1989 MscI, a type II restriction endonuclease from Micrococcus species which recognizes 5' TGGCCA 3'. Nucl.Acids Res. Polisson, C.
1989 Use of Degenerate Oligonucleotides for Amplification of the nifH Gene from the Marine Cyanobacterium Trichodesmium thiebautii. Appl.Environ.Microbiol., Zehr, J.P., and McReynolds, L.A.
1989 Nucleotide sequence of the FokI restriction-modification system: separate strand-specificity domains in the methyltransferase. Gene Looney, M.C., Moran, L.S., Jack, W.E., Feehery, G.R., Benner, J.S., Slatko, B.E., and Wilson, G.G.
1989 DrdI, a unique restriction endonuclease from Deinococcus radiodurans which recognizes 5'GACN6GTC3'. Nucl.Acids Res. Polisson, C., and Morgan, R.D.
1989 Cloning the BamHI restriction modification system. Nucl.Acids Res. Brooks, J.E., Benner, J.S., Heiter, D.F., Silber, K.R., Sznyter, L.A., Jager-Quinton, T., Moran, L.S., Slatko, B.E., Wilson, G.G., and Nwankwo, D.O.
1989 Genetic and physical mapping of the mcrA (rglA) and mcrB (rglB) loci of Escherichia coli K-12. Genetics Raleigh, E.A., Trimarchi, R., and Revel, H.
1989 Introduction of prokaryotic HhaI DNA methyltransferase alters the phenotype of 3T3 cells. Proc.Am.Assoc.Cancer Res. Herman, J., Nelkin, B., Mabry, M., Wilson, G., and Baylin, S.
1989 Human T-cell stimulation, molecular characterization and in situ mRNA localization of a Brugia malayi recombinant antigen. Mol.Biochem.Parasitol. Arasu, P., Nutman, T.B., Steel, C., Mulligan, M.M., Abraham, D., Tuan, R.S., and Perler, F.B.
1989 Site-directed mutagenesis of the EcoRV methylase for the study of the functional role of the conserved sequences in N6-adenine methylases J. Cell Biochem Barshevsky,T. and Benner J.S.
1989 Characterization of clones of the BamHI methyltransferase gene J. Cell Biochem. Nathan, P.D. and Brooks. J.E.
1988 AseI, a restriction endonuclease from Aquaspirillum serpens which recognizes 5'ATTAAT3'. Nucl.Acids Res. Polisson, C., and Morgan, R.D.
1988 Cloned restriction-modification systems - a review. Gene Wilson, G.G.
1988 BsrI, a unique restriction endonuclease from Bacillus stearothermophilus which recognizes 5'ACTGG3'. Nucl.Acids Res. Polisson, C., and Morgan, R.D.
1988 An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein. Gene Maina, C.V., Riggs, P.D., Grandea, A.G.I., Slatko, B.E., Moran, L.S., Tagliamonte, J.A., McReynolds, L.A., and Guan, C.D.
1988 Characterization of clones of the BamHI methyltransferase gene. Gene Nathan, P.D.and Brooks, J.E.
1988 A site-specific single strand endonuclease activity induced by NYs-1 virus infection of a Chlorella-like green alga. Nucl.Acids Res. Xia, Y., Morgan, R., Schildkraut, I., and Van Etten, J.L.
1988 Cloning and analysis of the HaeIII and HaeII methyltransferase genes. Gene Slatko, B.E., Croft, R., Moran, L.S., and Wilson, G.G.
1988 Cloning Type II restriction and modification genes. Gene Lunnen, K.D., Barsomian, J.M., Camp, R.R., Card, C.O., Chen, S.Z., Croft, R., Looney, M.C., Meda, M.M., Moran, L.S., Nwankwo, D.O., Slatko, B.E., Van Cott, E.M., and Wilson, G.G.
1988 EarI, a restriction endonuclease from Enterobacter aerogenes which recognizes 5'CTCTTC3'. Nucl.Acids Res. Polisson, C., and Morgan, R.D.
1988 Cloning the FnuDI, NaeI, NcoI and XbaI restriction-modification systems. Gene Van Cott, E.M., and Wilson, G.G.
1988 IMMUNITY IN FILARIASIS: Perspectives for Vaccine Development. Ann.Rev.Microbiol. Philipp, M., Davis , T.B., Storey, N., and Carlow, C.K.S.
1988 Genetic dissection of the methylcytosine-specific restriction system mcrB of Escherichia coli K-12. Gene Dila, D., and Raleigh, E.A.
1988 Cloning and sequencing the HinfI restriction and modification genes. Gene Chandrasegaran, S., Lunnen, K.D., Smith, H.O., and Wilson, G.G.
1988 Cloning of the HhaI and HinPI restriction-modification systems. Gene Barsomian, J.M., Card, C.O., and Wilson, G.G.
1988 Cloning and expression of the MspI restriction and modification genes. Gene Nwankwo, D.O., and Wilson, G.G.
1988 Cloning, purification and characterization of the M.NdeI methyltransferase from Neisseria denitrificans Gene Silber, K.R., Polisson, C., Rees, P.A., and Benner, J.S.
1988 Cloning, purification and characterization of the HincII and HindII methyltransferases from Haemophilus influenzae. Gene Rees, P.A., Nwankwo, D.O., Wilson, G.G., and Benner, J.S.
1988 The characterization and cloning of the EagI restriction-modification system. Gene Sznyter, L.A., and Brooks, J.E.
1988 The Amino Acid Sequence of the Eukaryotic DNA [N6-adenine] Methyltransferase, M-CviBIII, Has Regions of Similarity With the Prokaryotic Isoschizomer M-TaqI and Other DNA [N6-adenine] Methyltransferases. Gene Narva, K.E., Van Etten, J.L., Slatko, B.E.and Benner, J.S.
1988 Type II restriction-modification systems. Trends in Genetics Wilson, G.G.
1988 Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein. Gene Guan, C.D., Li, P., Riggs, P.D., and Inouye, H.
1988 McrA and McrB restriction phenotypes of some E.coli strains and implications for gene cloning. Nucl.Acids Res. Raleigh, E.A., Murray, N.E., Revel, H., Blumenthal, R.M., Westaway, D., Reith, A.D., Rigby, P.W.J., Elhai, J., and Hanahan, D.
1988 Isolation and characterization of restriction endonuclease BstYI from Bacillus stearothermophilus. FEBS Lett. Chen Z.and Kong, H.
1988 MseI, a unique restriction endonuclease from Micrococcus species which recognizes 5'T^TAA 3'. Nucl.Acids Res. Morgan, R.D.
1988 Species-specific oligonucleotide probes for the identification of human filarial parasites. Mol.Biochem.Parasitol. Williams, S.A., DeSimone, S.M., and McReynolds, L.A.
1988 Nomenclature for bacterial genes coding for class-II restriction endonucleases and modification methyltransferases. Gene Szybalski, W., Blumenthal, R.M., Brooks, J.E., Hattman, S., and Raleigh, E.A.
1988 Cloning and characterization of the BamHI restriction modification system Gene Brooks, J.E., Benner, J.S., Silber, K.R., Heiter, D.F., Sznyter, L.A., Jager-Quinton, T., Wilson, G.G., Moran, L.S., Slatko, B.E., Nwankwo, D.O.
1988 Isolation and properties of a new site specific endonuclease Bme142I from Bacillus megaterium Nucleic Acids Res. Fomenkov, A.I., Kramarov, V.M., Andreev, L.V., Mochalov, V.V., Smolyaninov, V.V., Matvienko, N.I.
1988 The characterization and cloning of the NotI restriction-modification system Heredity Sznyter, L.A., Brooks. J.E.
1987 NotI and SfiI: restriction endonucleases with octanucleotide recognition sequences. Methods Enzymol. Qiang, B.-Q., and Schildkraut, I.
1987 Properties and uses of restriction endonucleases. Methods Enzymol. Brooks, J.E.
1987 N4-Methylcytosine as a minor base in bacterial DNA. J.Bacteriol. Ehrlich, M., Wilson, G.G., Kenneth, C.K., and Gehrke, C.W.
1987 Nucleotide sequence of the DdeI restriction-modification system and characterization of the methylase protein. Nucl.Acids Res. Sznyter, L.A., Slatko, B., Moran, L., O'Donnell, K.H., and Brooks, J.E.
1987 Monoclonal antibody to a unique surface epitope of the human filaria Brugia malayi identifies infective larvae in mosquito vectors. Proc.Natl.Acad.Sci.USA Carlow, C.K.S., Franke, E.D., Lowrie, R.C.J., Partono, F., and Philipp, M.
1987 Highly Repeated DNA Sequences as Species-specific Probes for Brugia. Parasitology Today Piessens, W.F., McReynolds, L.A.and Williams, S.A.
1987 Genomic Cloning of Recombinant Antigens Detected by Antiserum Against Infective Larvae of Brugia Malayi. Molecular Paradigms for Eradicating Helminthic Parasites Arasu, P., and Perler, F.B.
1987 Monoclonal antibodies to parasite antigens: a rapid immunization protocol requiring small numbers of parasites. J.Parasitol. Carlow, C.K.S., Edwards, M.K., James, E.R., and Philipp, M.
1987 Isolation and Identification of restriction endonuclease BstFI Nucl.Acids Res. Kong, H and Chen, Z.
1987 The use of DNA methylases to alter the apparent recognition specificities of restriction endonucleases. Methods Enzymol. Nelson, M., and Schildkraut, I.