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    YearTitleJournalAuthorsApplication(s)
    2009Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection Bioconjug. Chem. Boeggeman, E., Ramakrishnan, B., Pasek, M., Manzoni, M., Puri, A., Loomis, K.H., Waybright, T.J., Qasba, P.K. Glycobiology
    1998Site-directed Mutagenesis of Essential Residues Involved in the Mechanism of Bacterial Glycosylasparaginase.J.Biol.Chem.Liu, Y., Guan, C.and Aronson, N.N., Jr.
    2004Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligationBioorg. Med. Chem. Lett.Takeda, S.,et al.
    2009Site-specific covalent labeling of proteins inside live cells using small molecule probesBioorg. Med. Chem.Chattopadhaya, S., et al.
    2005Site-specific DNA-nicking mutants of the heterodimeric restriction endonuclease R.BbvCI.J.Mol.Biol.Heiter, D.F., Lunnen, K.D.and Wilson, G.G.
    2005Site-specific immobilization of proteins in a microarray using intein-mediated protein splicingBioorg. Med. Chem. Lett.Girish, A., et al.
    2011Site-specific protein labeling by intein-mediated protein ligation.Methods Mol.Biol.Ghosh, I., Considine, N., Maunus, E., Sun, L., Zhang, A., Buswell, J., Evans, T.C.Jr.and Xu, M.Q.
    2009Site-Specific, covalent labeling of recombinant antibody fragments via fusion to an engineered version of 6-O-alkylguanine DNA alkyltransferaseBioconjug Chem. Kapmeier F. et al.
    2015Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylationNucleic Acids ResZhang, G., Esteve, P.O., Chin, H.G., Terragni, J., Dai, N., Correa, I.R. Jr. and Pradhan, S.
    2006SmpB triggers GTP hydrolysis of elongation factor Tu on ribosome by compensating for the lack of codon-anticodon interaction during trans-translation initiationJ. Biol. Chem.Shimizu, Y. and Ueda, T.
    2005SNAP-tag mediated live cell labeling as an alternative to GFP in anaerobic organismsBioTechniques Regoes A. et al.
    2008SNAP-tag Technologies: Novel tools to study protein functionNEB Expressions Johnson K.
    2004Soluble expression and affinity purification of functional domain of human acetylcholine receptor alpha-subunit by the modulation of maltose binding protein.Biotechnol Lett.Li, Z.Y., Li, Y.J., Guo, C.Y., Shi, Y.W., Xu, M-Q., Trommer, W.E.and Yuan, J.M.
    2009Soluble expression and one-step purification of a neurotoxin Huwentoxin-I in Escherichia coliProtein Expr Purif.Che, N., et. al.
    2007Solution Structure of a KlbA Intein Precursor from Methanococcus jannaschii.Protein Sci.Johnson, M., Southworth, M., Herrmann, T., Brace, L., Perler, F.and Wuthrich, K.
    1988Species-specific oligonucleotide probes for the identification of human filarial parasites.Mol.Biochem.Parasitol.Williams, S.A., DeSimone, S.M., and McReynolds, L.A.
    2004Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteinsMol. Cell Biol.Hemelaar, J.et al.
    2004Specific labeling of cell surface proteins with chemically diverse compoundsJ .Am. Chem. Soc.  George N. et al.
    2015Specificity of the ModAll, ModA12 and ModD1 epigenetic regulator N6-adenine DNA methyltransferases of Neisseria MeningitidisNucleic Acids ResSeib, K.L., Jen, F.E., Tan, A., Scott, A.L., Kumar, R., Power, P.M., Chen, L.T., Wu, H.J., Wang, A.H., Hill, D.M., Luyten, Y.A., Morgan, R.D., Roberts, R.J., Maiden, M.C., Boitano, M., Clark, T.A., Korlach, J., Rao, D.N. and Jennings, M.P.
    2008Spectral resolved gene technology for multiplexed bioluminescence and high content screening Anal. Chem. Michelini, E., Cevenini, L., Mezzanote, L., Ablamsky, D., Southworth, T., Branchini, B. and Roda, A.
    2014SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolutionProtein Eng Des SelCurrin A, Swainston N, Day PJ, Kell DB
    2010Splicing of the Mycobacteriophage Bethlehem DnaB intein: identification of a new mechanistic class of inteins that contain an obligate block F nucleophile.Journal of Biological ChemistryTori, K., Dassa, B., Johnson, M.A., Southworth, M.W., Brace, L.E., Ishino, Y., Pietrokovski, S., and Perler, F.B.
    2014Spontaneous in vitro senescence of glioma cells confirmed by an antibody against IDH1R132HAnticancer ResStoczynska-Fidelus E, Och W, Rieske P, Bienkowski M, Banaszczyk M, Winiecka-Klimek M, Zieba J, Janik K, Rosiak K, Treda C, Stawski R, Radomiak-Zaluska A, Piaskowski S
    2004SPR-based interaction studies with small molecular weight ligands using hAGT fusion proteinsAnal. Biochem. Huber W. et al.
    2010Stimulated emission depletion nanoscopy of living cells using SNAP-Tag fusion proteinsBiophys. J.  Hein B. et al.
    2014Strand Invasion Based Amplification (SIBA®): A Novel Isothermal DNA Amplification Technology Demonstrating High Specificity and Sensitivity for a Single Molecule of Target AnalytePLoS OneHoser MJ, Mansukoski HK, Morrical SW, Eboigbodin KE
    2009Strategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coliMicrobial Cell Factoriesde Marco, A.
    2015Structural and biochemical studies of a moderately thermophilic exonuclease I from Methylocaldum szegediensePLoS OneFei, L., Tian, S., Moysey, R., Misca, M., Barker, J.J., Smith, M.A., McEwan, P.A., Pilka, E.S., Crawley, L., Evans, T. and Sun, D.
    2014Structural basis for Klf4 recognition of methylated DNANucleic Acids ResearchYiwei Liu, Yusuf Olatunde Olanrewaju, Yu Zheng, Hideharu Hashimoto, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng
    2015Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15INature CommunicationsGupta, Y.K., Chan, S.H., Xu, S.Y., and Aggarwal, A.K.
    2012Structural bias in T4 RNA ligase-mediated 3'-adapter ligationNucleic Acids Res.Zhuang, F., Fuchs, R.T., Sun, Z., Zheng, Y. and Robb, G.B.
    2004Structural characterization and comparative phylogenetic analysis of E.coli HemK, a protein (N5)-glutamine methyltransferase.Mol.Microbiol.Yang, Z., Shipman, L., Zhang, M., Anton, B., Roberts, R.J.and Cheng, X.
    2012Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering J Mol biol. Gupta, Y.K., Yang, L., Chan, S.H., Samuelson, J.C., Xu, S.-Y. and Aggarwal, A.K.
    1999Structural Insights into the Mechanism of Intramolecular Proteolysis.CellXu, M.Q., Buckley, D., Guan, C.and Guo, H-C
    2000Structural Insights into the Protein Splicing Mechanism of PI-SceI.J.Biol.Chem.Poland, B.W., Xu, M.Q.and Quiocho, F.L.
    2006Structure and dynamics of the epidermal growth factor receptor C-terminal phosphorylation domainProtein Sci.Lee, N.Y., et al.
    2000Structure and function of the mouse DNA methyltransferase Gene, DNMT1 shows a tripartite structure.J.Mol.Biol.Margot, J.B., Aguirre-Arteta, A.M., DiGiacco, B.V., Pradhan, S., Roberts, R.J., Cardoso, M.C.and Leonhardt, H.
    2014Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHISci RepHorton JR, Nugent RL, Li A, Mabuchi MY, Fomenkov A, Cohen-Karni D, Griggs RM, Zhang X, Wilson GG, Zheng Y, Xu SY, Cheng X
    2014Structure of 5-hydroxymethylcytosine-specific restriction enzyme AbaSI in complex with DNANucleic Acids ResHorton JR, Borgaro JG, Griggs RM, Quimby A, Guan S, Zhang X, Wilson GG, Zheng Y, Zhu Z, Cheng X
    2014Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNANatureHashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ, Dai N, Corrêa IR Jr, Zheng Y, Cheng X
    2002Structure of a tRNA Repair Enzyme and Molecular Biology Workhorse: T4 Polynucleotide Kinase.StructureGalburt, E.A., Pelletier, J., Wilson, G.and Stoddard, B.L.
    1995Structure of BamHI endonuclease bound to DNA: partial folding and unfolding on DNA binding.ScienceNewman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
    1998Structure of FokI has Implications for DNA Cleavage.Proc.Natl.Acad.Sci.USA Wah, D.A., Bitinaite, J., Schildkraut, I., Aggarwal, A.K.
    2005Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI.Nucl.Acids.Res.Yang, Z., Horton, J.R., Maunus, R., Wilson, G.G., Roberts, R.R.and Cheng, X.
    1994Structure of PvuII endonuclease with cognate DNA.EMBO J.Cheng, X., Balendiran, K., Schildkraut, I., and Anderson, J.E.
    2003Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPaseScienceRak, A., et al.
    1994Structure of restriction endonuclease BamHI and its relationship to EcoRI.NatureNewman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
    1994Structure of restriction endonuclease BamHI phased at 1.95 A resolution by MAD analysis.StructureNewman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
    2003Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexesProc. Natl. Acad. Sci. USASinars, C.R., et al.
    1997Structure of the Multimodular Endonuclease FokI Bound to DNA.NatureWah, D.A., Hirsch, J.A., Dorner, L.F., Schildkraut, I., Aggarwal, A.K.
    2004Structure of the Q237W mutant of HhaI DNA methyltransferase: An insight into protein-protein interactions.Biol.Chem.Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J.and Cheng, X.
    2014Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic DrugsPLoS PathogFarelli JD, Galvin BD, Li Z, Liu C, Aono M, Garland M, Hallett OE, Causey TB, Ali-Reynolds A, Saltzberg DJ, Carlow CK, Dunaway-Mariano D, Allen KN
    2012Structure-function analysis of Methanobacterium thermoautotrophicum RNA ligase - engineering a thermostable ATP independent enzymeBMC Mol Biol.Zhelkovsky, A.M. and McReynolds, L.A.
    1999Structures of a Binary Complex of HhaI Methyltransferase with S-adenosyl-L-methionine Formed in the Presence of a Short Non-specific DNA Oligonucleotide.J.Mol.Biol.O'Gara, M., Zhang, X., Roberts, R.J.and Cheng, X.
    1998Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.Nature Struct.Biol.O'Gara, M., Horton, J.R., Roberts, R.J.and Cheng, X.
    2008Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding.StructureLambert, A.R., Sussman, D., Shen, b., Maunus, R., Nix, J., Samuelson, J., Xu, S.Y.and Stoddard, B.L.
    2012Stucture and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.Nucleic Acids ResearchHorton, J.R., Mabuchi, M., Cohen-Karni, D., Zhang, X., Griggs, R., Samaranayake, M., Roberts, R.J., Zheng, Y. and Cheng, X.
    2003Study of protein splicing and intein-mediated peptide bond cleavage under high-cell-density conditions.Biotechnol.Prog.Sharma, S., Zhang, A., Wang, H., Harcum, S.W.and Chong S.
    2012Substrate cooperativity in marine luciferasesPLoS OneTzertzinis, G., Schildkraut, E., and Schildkraut, I.
    2012Substrate cooperativity in marine luciferases PLoS OneTzertzinis, G., Schildkraut, E. and Schildkraut, I.
    1997Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, Bcgl.Nucl.Acids Res.Kong, H., and Smith, C.L.
    2004Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.J.Biol.Chem.Patnaik, D., chin, H.G., esteve, P.O., Benner, J., Jacobsen, S.E.and Pradhan, S.
    2013Substrates for Improved Live-Cell Fluorescence Labeling of SNAP-tagCurrent Pharmaceutical DesignIvan R. Corrêa Jr, Brenda Baker, Aihua Zhang, Luo Sun, Christopher R. Provost, Grazvydas Lukinavicius, Luc Reymond, Kai Johnsson, and Ming-Qun Xu
    2007Subtilisin-like proteases in nematodes.Mol.Biochem.Parasitol.Poole, C.B., Jin, J.and McReynolds, L.A.
    2008Subunit-specific surface mobility of differentially labeled AMPA receptor subunitsEur. J. Cell Biol. Kropf M. et al.
    2015Sul1 and Sul2 Sulfate Transceptors Signal to Protein Kinase A upon Exit of Sulfur Starvation.J Biol ChemHarish Nag Kankipati, Marta Rubio-Texeira, Dries Castermans, George Diallinas, Johan M TheveleinHigh-Fidelity PCR
    2004Synthesis and characterization of bifunctional probes for the specific labeling of fusion proteinsBioorg. Med. Chem. Lett. Kindermann M. et al.
    2006Synthesis and evaluation of the bioluminescent activity of (S)-Cypridina luciferin and its analogsTetrahedron LettersWu, C., Kawasaki, K., Ohgiya, S., Ohmiya, Y.
    2004Synthesis of fluorescently labeled mono- and diprenylated Rab7 GTPaseJ. Am. Chem. Soc.Durek, T., et al.
    2007Synthesis of Polyester by Means of Genetic Code ReprogrammingChem. Biol. Ohta, A., Murakami, H., Higashimura, E., and Suga, H.
    2007Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayersJ. Am. Chem. Soc. Paulick, M. G., et al.
    2011T4 RNA ligase 2 truncated active site mutants: improved tools for RNA analysis.BMC Biotechnol.Viollet, S., Fuchs, R.T., Munafo, D.B., Zhuang, F.and Robb, G.B.
    2009Tag-probe labeling methods for live-cell imaging of membrane proteins Biochim. Biophys. Acta. Uano Y. and Matsuzaki K.
    2015TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy.J Clin InvestZheng Hu, Wencheng Ding, Da Zhu, Lan Yu, Xiaohui Jiang, Xiaoli Wang, Changlin Zhang, Liming Wang, Teng Ji, Dan Liu, Dan He, Xi Xia, Tao Zhu, Juncheng Wei, Peng Wu, Changyu Wang, Ling Xi, Qinglei Gao, Gang Chen, Rong Liu, Kezhen Li, Shuang Li, Shixuan Wang, Jianfeng Zhou, Ding Ma, Hui Wang Genome Editing
    2013Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survivalProc. Natl. Acad. Sci. Cieslewicz, M. et alPhage Display
    2013Targeted drug delivery systems mediated by a novel peptide in breast cancer therapy and imagingPLoS OneLu, R.-M. et alPhage Display
    2012Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNASymbiosisGeniez, S., Foster, J.M., Kumar, S., Moumen, B., Leproust, E., Hardy, O., Guadalupe, M., Thomas, S.J., Boone, B., Hendrickson, C., Bouchon, D., Greve, P and Slatko, B.E.
    2008Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinomaPLoS Med.Kelly, K.A. et al.
    2010Targeted photoswitchable probe for nanoscopy of biological structures ChemBioChem Dellagiacoma, C. et al.
    2011Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous systemBMC NeurosciGonzalez, A.M. et al.Phage Display
    2008Targeting DNA (5)mCpG sites with chimeric endonucleases.Anal.Biochem.Formenkov, A., Too, P.H., Chan, S.H., Vaisvila, R., Cantin, B.A., Mazzola, L., Tam, V.and Xu, S.Y.
    2010Targeting of embryonic stem cells by peptide-conjugated quantum dotsPLoS OneLu, S. et al.
    2009Targeting of tumor blood vessels: a phage-displayed tumor-homing peptide specifically binds to matrix metalloproteinase-2-processed collagen IV and blocks angiogenesis in vivoMol. Cancer Res.Mueller, J. et al.
    2011Targeting the Wolbachia Cell Division Protein FtsZ as a New Approach for Antifilarial Therapy.PLoS Neglected Tropical DiseasesLi, Z., Garner, A.L., Gloeckner, C., Janda, K.D.and Carlow, C.K.
    2007Tasting Phenylthiocarbamide (PTC): A New Lab With an Old Flavor.Am.Biol.Teacher Merritt, R., Bierwort, L., Slatko, B., Weiner, M., Weiner, E., Ingram, J.and Sciarra, K.
    2008Tasting Phenylthiocarbamide (PTC): A New Lab With an Old Flavor.Am.Biol.TeacherMerritt, R., Bierwort, L., Slatko, B., Weiner, M., Weiner, E., Ingram, J.and Sciarra, K.
    1996Teaching About ScienceAccountability in ResearchRoberts, R.J.
    2008Templated protein assembly on micro-contact-printed surface patterns. Use of the SNAP-tag protein functionality LangumuirIversen L. et al.
    2008Template-Independent DNA Polymerases.Curr.Protoc.Mol.Biol.Yue, D., Tabor, S.and Nichols, N.M.
    2015Ten simple rules to win a nobel prizeRoberts, R.J.
    2013The advantages of SMRT™ sequencing.  Genome Biology Roberts, R.J., Carneiro, M.O., Schatz, M.C.
    2014The ambrosia symbiosis is specific in some species and promiscuous in others: evidence from community pyrosequencing.ISME JMartin Kostovcik, Craig C Bateman, Miroslav Kolarik, Lukasz L Stelinski, Bjarte H Jordal, Jiri HulcrHigh-Fidelity PCR
    1988The Amino Acid Sequence of the Eukaryotic DNA [N6-adenine] Methyltransferase, M-CviBIII, Has Regions of Similarity With the Prokaryotic Isoschizomer M-TaqI and Other DNA [N6-adenine] Methyltransferases.GeneNarva, K.E., Van Etten, J.L., Slatko, B.E.and Benner, J.S.
    2009The apearance of pyrrolysine in tRNAHis guanylyltransferase by neutral evolution.Proc.Natl.Acad.Sci.USAHeinemann, I.U., O'donoghue, P., Madinger, C., Benner, J., Randau, L., Noren, C.J.and Soll, D.
    2011The Arthrobacter Species FB24 Arth_1007 (DnaB) Intein Is a Pseudogene.PLoS ONETori, K.and Perler, F.B.
    2004The bacterial catalase from filarial DNA preparations derives from common pseudomonad contaminants and not from Wolbachia endosymbionts.Parasitol.Res.Foster, J., Baldo, L., Blaxter, M., Hendle-Duhrsen, K., Whitton, C., Slatko, B.and Bandi, C
    2008The BsaHI restriction-modification system: Cloning, sequencing and characterisation of DNA recognising motifs.BMC Molecular Biology Neely, R.K.and Roberts, R.J.
    2008The Caenorhabditis elegans NR4A nuclear receptor is required for spermatheca morphogenesis.Dev.Biol.Gissendanner, C.R., Kelley, K., Nguyen, T.Q., Hoener, M.C., Sluder, A.E.and Maina, C.V.
    1988The characterization and cloning of the EagI restriction-modification system.Gene Sznyter, L.A., and Brooks, J.E.
    2011The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes Biochem J.  Panayiotou, C., Solaroli, N., Xu, Y., Johansson, M. and Karlsson, A.